SCHEMBL10326440

SCHEMBL10326440

c1ccc(-c2ccc(C(c3ccc(-c4ccccc4)cc3)[C@@H]3CCCN3)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 10/20 0.47
SLC6A2 P23975 8/20 0.47
SLC6A4 P31645 8/20 0.47
DHFR P00374 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10326261 1.00 SLC6A3 (0.47) SLC6A3SLC6A2SLC6A4DHFR
SCHEMBL10326717 1.00 SLC6A3 (0.47) SLC6A3SLC6A2SLC6A4DHFR
SCHEMBL9915339 0.98 SLC6A3 (0.47) SLC6A3SLC6A2SLC6A4DHFR
SCHEMBL12996843 0.98 SLC6A3 (0.47) SLC6A3SLC6A2SLC6A4DHFR
SCHEMBL10326911 0.95 SLC6A3 (0.54) SLC6A3SLC6A2SLC6A4DHFR
SCHEMBL10327324 0.95 SLC6A3 (0.54) SLC6A3SLC6A2SLC6A4DHFR
SCHEMBL10326624 0.95 SLC6A3 (0.54) SLC6A3SLC6A2SLC6A4DHFR
SCHEMBL2844473 0.89 SLC6A3 (0.53) SLC6A3SLC6A2SLC6A4DHFR
SCHEMBL2842321 0.89 SLC6A3 (0.53) SLC6A3SLC6A2SLC6A4DHFR
SCHEMBL670331 0.89 SLC6A3 (0.53) SLC6A3SLC6A2SLC6A4DHFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8217204-B2 Catalyst for asymmetric hydrogenation TAKASAGO INTERNATIONAL CORPORATION (JP) 2012-07-10 US disclosed
US-8217204-B2 Catalyst for asymmetric hydrogenation TAKASAGO INTERNATIONAL CORPORATION (JP) 2012-07-10 US disclosed
US-20100324338-A1 CATALYST FOR ASYMMETRIC HYDROGENATION TAKASAGO INTERNATIONAL CORPORATION (JP) 2010-12-23 US disclosed
US-20100324338-A1 CATALYST FOR ASYMMETRIC HYDROGENATION TAKASAGO INTERNATIONAL CORPORATION (JP) 2010-12-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100324338-A1 CATALYST FOR ASYMMETRIC HYDROGENATION H1-0, H1-5, ADH5 SLC6A3 4843/4885SLC6A2 4820/4885SLC6A4 4697/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.