Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 7/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.57 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2622619 | 0.92 | ALDH1A1 (0.65) | APPALDH1A1ALDH3A1ALDH1A3MAPT | |
| SCHEMBL11876851 | 0.85 | APP (0.95) | APPALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9017237 | 0.85 | APP (0.95) | APPALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9017239 | 0.85 | APP (0.95) | APPALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11876857 | 0.85 | APP (0.95) | APPALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2622630 | 0.85 | ALDH1A1 (0.57) | APPALDH1A1ALDH3A1ALDH1A3MAPT | |
| SCHEMBL2622641 | 0.85 | ALDH1A1 (0.57) | APPALDH1A1ALDH3A1ALDH1A3MAPT | |
| SCHEMBL2622612 | 0.85 | ALDH1A1 (0.57) | APPALDH1A1ALDH3A1ALDH1A3MAPT | |
| SCHEMBL9017226 | 0.84 | APP (0.50) | APPALDH1A1ALDH3A1ALDH1A3MAPT | |
| SCHEMBL2298605 | 0.83 | ALDH1A1 (0.71) | ALDH1A1ALDH3A1ALDH1A3MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8197722-B2 | Irradiating the compound (containing two electron donor groups and a bridge of pi-conjugated bonds containing electron donor groups) with light, and the compound is converted to a multi-photon electronically excited state | THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-06-12 | — | — | US | disclosed |
| US-8197722-B2 | Irradiating the compound (containing two electron donor groups and a bridge of pi-conjugated bonds containing electron donor groups) with light, and the compound is converted to a multi-photon electronically excited state | THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-06-12 | — | — | US | disclosed |