Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.51 |
| ▸ | MEN1 | O00255 | 8/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TNFRSF1A | P19438 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9915864 | 0.90 | MEN1 (0.49) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL13559205 | 0.74 | MEN1 (0.53) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL14712993 | 0.73 | MEN1 (0.57) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL13559209 | 0.73 | MEN1 (0.42) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL9329273 | 0.70 | PDE4B (0.42) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL29165202 | 0.69 | TNFRSF1A (0.50) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL30788739 | 0.69 | TNFRSF1A (0.62) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL15592638 | 0.68 | MAPT (0.63) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL10014431 | 0.67 | MAPT (0.53) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL11149658 | 0.66 | TNFRSF1A (0.56) | MAPTMEN1KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8197722-B2 | Irradiating the compound (containing two electron donor groups and a bridge of pi-conjugated bonds containing electron donor groups) with light, and the compound is converted to a multi-photon electronically excited state | THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-06-12 | — | — | US | disclosed |