Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 6/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.40 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.40 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | HMGCR | P04035 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9915852 | 0.90 | MAPT (0.51) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL15592579 | 0.67 | ALDH1A1 (0.49) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL10202019 | 0.65 | MAPT (0.60) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL11314234 | 0.65 | TNFRSF1A (0.50) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL16967442 | 0.64 | KMT2A (0.62) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL10195153 | 0.64 | EP300 (0.53) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL9915849 | 0.64 | ALDH1A1 (0.78) | MAPTALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL2680644 | 0.64 | F2 (0.55) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL14713062 | 0.64 | NR1H3 (0.41) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL14712993 | 0.63 | MEN1 (0.57) | MEN1KMT2AMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8197722-B2 | Irradiating the compound (containing two electron donor groups and a bridge of pi-conjugated bonds containing electron donor groups) with light, and the compound is converted to a multi-photon electronically excited state | THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-06-12 | — | — | US | disclosed |