SCHEMBL13559205

SCHEMBL13559205

CCN1C(=O)C(=Cc2cc(O)c(C=C3C(=O)N(CC)C(=S)N(CC)C3=O)cc2O)C(=O)N(CC)C1=S

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.53
KMT2A Q03164 7/20 0.53
MAPT P10636 6/20 0.53
ALDH1A1 P00352 5/20 0.53
HTT P42858 2/20 0.53
TNFRSF1A P19438 6/20 0.52
MAPK1 P28482 2/20 0.51
POLB P06746 2/20 0.51
HPGD P15428 2/20 0.51
LMNA P02545 2/20 0.51
NPC1 O15118 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
ENPP3 O14638 1/20 0.46
MDM2 Q00987 3/20 0.45
NPSR1 Q6W5P4 1/20 0.42
KDM4E B2RXH2 2/20 0.42
THRB P10828 1/20 0.42
KDM4C Q9H3R0 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
STAT3 P40763 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12436626 0.75 EP300 (0.49) MEN1KMT2AMAPTALDH1A1HTT
SCHEMBL14419270 0.74 MAPT (0.51) MEN1KMT2AMAPTALDH1A1HTT
SCHEMBL9915852 0.74 MAPT (0.51) MEN1KMT2AMAPTALDH1A1HTT
SCHEMBL30788739 0.74 TNFRSF1A (0.62) MEN1KMT2AMAPTALDH1A1HTT
SCHEMBL15592638 0.73 MAPT (0.63) MEN1KMT2AMAPTALDH1A1HTT
SCHEMBL10014431 0.72 MAPT (0.53) MEN1KMT2AMAPTALDH1A1HTT
SCHEMBL11149658 0.71 TNFRSF1A (0.56) MEN1KMT2AMAPTALDH1A1HTT
SCHEMBL29165166 0.71 TNFRSF1A (0.50) MEN1KMT2AMAPTALDH1A1HTT
SCHEMBL29165195 0.71 TNFRSF1A (0.46) MEN1KMT2AMAPTALDH1A1HTT
SCHEMBL25165746 0.71 ALDH1A1 (0.51) MEN1KMT2AMAPTALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9012230-B2 Fluorescent nanoprobe for detecting hydrogen peroxide and fabrication method thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2015-04-21 US disclosed
US-9012230-B2 Fluorescent nanoprobe for detecting hydrogen peroxide and fabrication method thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2015-04-21 US disclosed
US-20120276651-A1 FLUORESCENT NANOPROBE FOR DETECTING HYDROGEN PEROXIDE AND FABRICATION METHOD THEREOF KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2012-11-01 US disclosed
US-20120276651-A1 FLUORESCENT NANOPROBE FOR DETECTING HYDROGEN PEROXIDE AND FABRICATION METHOD THEREOF KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2012-11-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120276651-A1 FLUORESCENT NANOPROBE FOR DETECTING HYDROGEN PEROXIDE AND FABRICATION METHOD THEREOF GPX4, PPOX, SQOR MEN1 4617/4885KMT2A 3294/4885MAPT 4477/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.