Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 17/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL990821 | 0.85 | GRM5 (0.44) | GRM5 | |
| SCHEMBL990968 | 0.84 | GRM5 (0.45) | GRM5L3MBTL1RAB9A | |
| SCHEMBL990400 | 0.84 | GRM5 (0.43) | GRM5L3MBTL1KDM4EALDH1A1GAA | |
| SCHEMBL992162 | 0.83 | GRM5 (0.56) | GRM5 | |
| SCHEMBL990845 | 0.83 | GRM5 (0.56) | GRM5 | |
| SCHEMBL1898596 | 0.83 | GRM5 (0.46) | GRM5L3MBTL1NPC1RAB9A | |
| SCHEMBL992121 | 0.83 | GRM5 (0.43) | GRM5L3MBTL1NPC1RAB9A | |
| SCHEMBL990983 | 0.82 | GRM5 (0.42) | GRM5L3MBTL1NPC1RAB9A | |
| SCHEMBL990340 | 0.82 | L3MBTL1 (0.59) | GRM5L3MBTL1NPC1RAB9A | |
| SCHEMBL990840 | 0.82 | GRM5 (0.60) | GRM5L3MBTL1ALDH1A1GAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2272509-A1 | New Uses of metabotropic glutamate receptors | Novartis AG (CH) | 2011-01-12 | — | — | EP | disclosed |