Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CAD | P27708 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL964570 | 0.83 | LMNA (0.50) | L3MBTL1ALDH1A1LMNAHSD17B10MGAM | |
| SCHEMBL9917049 | 0.83 | CYP2C9 (0.50) | CYP2C9ALDH1A1LMNAKMT2APOLB | |
| SCHEMBL3032954 | 0.78 | LMNA (0.43) | L3MBTL1ALDH1A1LMNAHSD17B10MGAM | |
| SCHEMBL3023544 | 0.78 | HCRTR2 (0.47) | ALDH1A1LMNAGAAKMT2APOLB | |
| SCHEMBL12160531 | 0.77 | TGFBR1 (0.42) | L3MBTL1ALDH1A1LMNAHSD17B10MGAM | |
| SCHEMBL10530552 | 0.77 | PSMB5 (0.46) | CYP2C9L3MBTL1ALDH1A1LMNAMGAM | |
| SCHEMBL14786634 | 0.77 | ALDH1A1 (0.44) | CYP2C9L3MBTL1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL21393378 | 0.77 | ALDH1A1 (0.44) | CYP2C9L3MBTL1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL31501278 | 0.77 | CYP2C9 (0.45) | CYP2C9ALDH1A1LMNAGAAKMT2A | |
| SCHEMBL8992064 | 0.76 | LMNA (0.41) | CYP2C9ALDH1A1LMNAHSD17B10CAD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119708525-A | Superfine grain tungsten-based composite material and preparation method thereof | 江西澳科新材料科技股份有限公司 | 2025-03-28 | — | — | CN | claimed |
| CN-119708525-A | Superfine grain tungsten-based composite material and preparation method thereof | 江西澳科新材料科技股份有限公司 | 2025-03-28 | — | — | CN | disclosed |
| US-8304419-B2 | Chemical compounds | GLAXOSMITHKLINE LLC (US) | 2012-11-06 | — | — | US | disclosed |
| US-20100216746-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2010-08-26 | — | — | US | disclosed |
| EP-2166856-A1 | CHEMICAL COMPOUNDS | GlaxoSmithKline LLC (US) | 2010-03-31 | — | — | EP | disclosed |
| WO-2008154271-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-12-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216746-A1 | CHEMICAL COMPOUNDS | SAMHD1, POLRMT, NUDT1 | CYP2C9 720/4885L3MBTL1 1657/4885ALDH1A1 348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.