Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL28841659 | 0.89 | GLRA1 (0.91) | — | |
| Glycine SCHEMBL27969394 | 0.89 | — | — | |
| Glycine SCHEMBL28314139 | 0.86 | — | — | |
| Glycine SCHEMBL30844145 | 0.86 | GLRA1 (0.71) | — | |
| Glycine SCHEMBL456097 | 0.86 | — | — | |
| Glycine SCHEMBL6675874 | 0.84 | GLRA1 (1.00) | — | |
| Glycine SCHEMBL93765 | 0.84 | GLRA1 (1.00) | — | |
| Glycine SCHEMBL2116443 | 0.84 | — | — | |
| Glycine SCHEMBL3640989 | 0.84 | GLRA1 (1.00) | — | |
| Glycine SCHEMBL391786 | 0.84 | GLRA1 (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9212122-B2 | Process for inhibiting unwanted free-radical polymerization of acrylic acid present in a liquid phase P | BASF SE (DE) | 2015-12-15 | — | — | US | disclosed |
| US-9096513-B2 | — | — | 2015-08-04 | — | — | US | disclosed |
| EP-2625159-A1 | PROCESS FOR INHIBITING UNWANTED FREE-RADICAL POLYMERIZATION OF ACRYLIC ACID PRESENT IN A LIQUID PHASE P | BASF SE (DE) | 2013-08-14 | — | — | EP | disclosed |
| WO-2012045738-A1 | PROCESS FOR INHIBITING UNWANTED FREE-RADICAL POLYMERIZATION OF ACRYLIC ACID PRESENT IN A LIQUID PHASE P | BASF SE (DE) | 2012-04-12 | — | — | WO | disclosed |
| US-20120085969-A1 | PROCESS FOR INHIBITING UNWANTED FREE-RADICAL POLYMERIZATION OF ACRYLIC ACID PRESENT IN A LIQUID PHASE P | BASF SE (DE) | 2012-04-12 | — | — | US | disclosed |
| WO-2011006065-A2 | AQUEOUS FLUOROPOLYMER COATING COMPOSITION AND COATED ARTICLES MADE USING SUCH COMPOSITION | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-01-13 | — | — | WO | disclosed |