Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9918118 | 0.81 | NR1H2 (0.42) | ALDH1A1TDP1CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL272396 | 0.78 | ESR1 (0.43) | ALDH1A1CYP3A4CYP2C19MAPTNR1H2 | |
| SCHEMBL9918117 | 0.77 | ALDH1A1 (0.39) | ALDH1A1TDP1CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL8514131 | 0.76 | ALDH1A1 (0.35) | ALDH1A1TDP1CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL25672890 | 0.72 | ALDH1A1 (0.41) | ALDH1A1TDP1CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL9918120 | 0.72 | ALDH1A1 (0.36) | ALDH1A1TDP1CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL8516060 | 0.71 | CYP1A2 (0.35) | ALDH1A1TDP1CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL25673074 | 0.69 | ALDH1A1 (0.43) | ALDH1A1TDP1CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL5858491 | 0.69 | ALDH1A1 (0.55) | ALDH1A1TDP1CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL12936130 | 0.69 | ALDH1A1 (0.55) | ALDH1A1TDP1CYP2D6CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8575384-B2 | Silanol-containing triarylamine derivatives | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-11-05 | — | — | US | disclosed |
| US-8575384-B2 | Silanol-containing triarylamine derivatives | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-11-05 | — | — | US | disclosed |
| US-20120149913-A1 | SILANOL-CONTAINING TRIARYLAMINE DERIVATIVES | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149913-A1 | SILANOL-CONTAINING TRIARYLAMINE DERIVATIVES | SIK2, AS3MT, ILK | ALDH1A1 1233/4885TDP1 2831/4885CYP2D6 2867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.