Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8514131 | 0.91 | ALDH1A1 (0.35) | ALDH1A1CYP3A4CYP2C9CYP2C19MAPT | |
| SCHEMBL8516060 | 0.88 | CYP1A2 (0.35) | ALDH1A1PKMCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13886460 | 0.80 | ALDH1A1 (0.48) | SLC6A2SLC6A4ALDH1A1RAB9ANPC1 | |
| SCHEMBL22812841 | 0.80 | ALDH1A1 (0.48) | SLC6A2SLC6A4ALDH1A1RAB9ANPC1 | |
| SCHEMBL13017732 | 0.80 | ALDH1A1 (0.48) | SLC6A2SLC6A4ALDH1A1RAB9ANPC1 | |
| SCHEMBL10039954 | 0.80 | ALDH1A1 (0.48) | SLC6A2SLC6A4ALDH1A1RAB9ANPC1 | |
| SCHEMBL10065627 | 0.80 | ALDH1A1 (0.48) | SLC6A2SLC6A4ALDH1A1RAB9ANPC1 | |
| SCHEMBL13844494 | 0.80 | ALDH1A1 (0.48) | SLC6A2SLC6A4ALDH1A1RAB9ANPC1 | |
| SCHEMBL13720602 | 0.80 | ALDH1A1 (0.48) | SLC6A2SLC6A4ALDH1A1RAB9ANPC1 | |
| SCHEMBL10065551 | 0.80 | ALDH1A1 (0.48) | SLC6A2SLC6A4ALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8575384-B2 | Silanol-containing triarylamine derivatives | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-11-05 | — | — | US | disclosed |
| US-8575384-B2 | Silanol-containing triarylamine derivatives | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-11-05 | — | — | US | disclosed |
| US-20120149913-A1 | SILANOL-CONTAINING TRIARYLAMINE DERIVATIVES | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149913-A1 | SILANOL-CONTAINING TRIARYLAMINE DERIVATIVES | SIK2, AS3MT, ILK | SLC6A2 1172/4885SLC6A4 1091/4885ALDH1A1 1233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.