SCHEMBL9920564

SCHEMBL9920564

Cc1ccc2c(c1)c1cc(C)ccc1n2-c1ccc2c(c1)c1cc([Si](c3ccccc3)(c3ccccc3)c3ccccc3)ccc1n2-c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
ATM Q13315 1/20 0.39
FGFR1 P11362 1/20 0.38
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
NR1I2 O75469 1/20 0.37
AHR P35869 1/20 0.37
ALDH1A1 P00352 3/20 0.36
HPGD P15428 3/20 0.36
TSHR P16473 2/20 0.36
HSD17B10 Q99714 2/20 0.36
MAPK1 P28482 1/20 0.36
CASP1 P29466 1/20 0.36
CASP7 P55210 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
BCHE P06276 1/20 0.35
ACHE P22303 1/20 0.35
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12879548 0.96 KDM4E (0.38) KDM4EL3MBTL1ATMFGFR1KMT2A
SCHEMBL25648189 0.96 KDM4E (0.42) KDM4EL3MBTL1ATMFGFR1KMT2A
SCHEMBL17463239 0.93 KDM4E (0.49) KDM4EL3MBTL1ATMFGFR1KMT2A
SCHEMBL22907506 0.93 FGFR1 (0.39) KDM4EL3MBTL1ATMFGFR1KMT2A
SCHEMBL12879567 0.93 FGFR1 (0.39) KDM4EL3MBTL1ATMFGFR1KMT2A
SCHEMBL12879639 0.91 KDM4E (0.46) KDM4EL3MBTL1ATMKMT2AMEN1
SCHEMBL17463390 0.90 AVPR1A (0.40) KDM4EL3MBTL1ATMFGFR1KMT2A
SCHEMBL12879568 0.90 FGFR1 (0.38) KDM4EL3MBTL1ATMFGFR1KMT2A
SCHEMBL25449262 0.89 L3MBTL1 (0.44) KDM4EL3MBTL1ATMFGFR1KMT2A
SCHEMBL22907507 0.89 L3MBTL1 (0.44) KDM4EL3MBTL1ATMFGFR1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11839140-B2 Metal complexes comprising diazabenzmidazolocarbene ligands and the use thereof in OLEDS UDC IRELAND LIMITED (IE) 2023-12-05 US disclosed
US-20220144869-A1 HETEROLEPTIC CARBENE COMPLEXES AND THE USE THEREOF IN ORGANIC ELECTRONICS UDC IRELAND LIMITED (IE) 2022-05-12 US disclosed
US-11189806-B2 Heteroleptic carbene complexes and the use thereof in organic electronics UDC IRELAND LIMITED (IE) 2021-11-30 US disclosed
US-20200373503-A1 HETEROLEPTIC CARBENE COMPLEXES AND THE USE THEREOF IN ORGANIC ELECTRONICS BASF SE (DE) 2020-11-26 US disclosed
EP-2393819-B9 SILYL AND HETEROATOM SUBSTITUTED COMPOUNDS SELECTED FROM CARBAZOLES, DIBENZOFURANS, DIBENZOTHIOPHENES AND DIBENZO PHOSPHOLES AND THE APPLICATION THEREOF IN ORGANIC ELECTRONICS UDC IRELAND LTD (IE) 2017-12-27 EP disclosed
US-20170025626-A1 Metal Complexes Comprising Diazabenzmidazolocarbene Ligands and the Use Thereof in OLEDS UDC IRELAND LTD (IE) 2017-01-26 US disclosed
EP-2393819-B1 SILYL AND HETEROATOM SUBSTITUTED COMPOUNDS SELECTED FROM CARBAZOLES, DIBENZOFURANS, DIBENZOTHIOPHENES AND DIBENZO PHOSPHOLES AND THE APPLICATION THEREOF IN ORGANIC ELECTRONICS BASF SE (DE) 2017-01-25 EP disclosed
US-9487548-B2 Metal complexes comprising diazabenzimidazolocarbene ligands and the use thereof in OLEDs UDC IRELAND LIMITED (IE) 2016-11-08 US disclosed
US-9458182-B2 Silyl- and heteroatom-substituted compounds selected from carbazoles, dibenzofurans, dibenzothiophenes and dibenzophospholes, and use thereof in organic electronics BASF SE (DE) 2016-10-04 US disclosed
US-9458182-B2 Silyl- and heteroatom-substituted compounds selected from carbazoles, dibenzofurans, dibenzothiophenes and dibenzophospholes, and use thereof in organic electronics BASF SE (DE) 2016-10-04 US disclosed
US-9315724-B2 Metal complexes comprising azabenzimidazole carbene ligands and the use thereof in OLEDs BASF SE (DE) 2016-04-19 US disclosed
EP-2493906-B1 HETEROLEPTIC CARBEN COMPLEXES AND THEIR USE IN ORGANIG ELECTRONICS BASF SE (DE) 2015-10-21 EP disclosed
US-8691401-B2 Bridged benzimidazole-carbene complexes and use thereof in OLEDS BASF SE (DE) 2014-04-08 US disclosed
US-20130032766-A1 METAL COMPLEXES COMPRISING DIAZABENZIMIDAZOLOCARBENE LIGANDS AND THE USE THEREOF IN OLEDS BASF SE (DE) 2013-02-07 US disclosed
US-8362246-B2 Bispyrimidines for electronic applications BASF SE (DE) 2013-01-29 US disclosed
US-20120319050-A1 METAL COMPLEXES COMPRISING AZABENZIMIDAZOLE CARBENE LIGANDS AND THE USE THEREOF IN OLEDS BASF SE (DE) 2012-12-20 US disclosed
US-20120205645-A1 HETEROLEPTIC CARBENE COMPLEXES AND THE USE THEREOF IN ORGANIC ELECTRONICS BASF SE (DE) 2012-08-16 US disclosed
US-20120149904-A1 BISPYRIMIDINES FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2012-06-14 US disclosed
US-20120012821-A1 SILYL- AND HETEROATOM-SUBSTITUTED COMPOUNDS SELECTED FROM CARBAZOLES, DIBENZOFURANS, DIBENZOTHIOPHENES AND DIBENZOPHOSPHOLES, AND USE THEREOF IN ORGANIC ELECTRONICS BASF SE (DE) 2012-01-19 US disclosed
US-20110253988-A1 BRIDGED BENZIMIDAZOLE-CARBENE COMPLEXES AND USE THEREOF IN OLEDS BASF SE (DE) 2011-10-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120319050-A1 METAL COMPLEXES COMPRISING AZABENZIMIDAZOLE CARBENE LIGANDS AND THE USE THEREOF IN OLEDS OCIAD1, OCIAD2, OXA1L KDM4E 4412/4885L3MBTL1 3381/4885ATM 3454/4885
US-20120205645-A1 HETEROLEPTIC CARBENE COMPLEXES AND THE USE THEREOF IN ORGANIC ELECTRONICS OCIAD2, OCIAD1, CLTB KDM4E 3813/4885L3MBTL1 1656/4885ATM 4500/4885
US-20120149904-A1 BISPYRIMIDINES FOR ELECTRONIC APPLICATIONS DPYD, TYMP, TYMS KDM4E 1622/4885L3MBTL1 3766/4885ATM 2950/4885
US-20220144869-A1 HETEROLEPTIC CARBENE COMPLEXES AND THE USE THEREOF IN ORGANIC ELECTRONICS OCIAD2, OCIAD1, CLTB KDM4E 4143/4885L3MBTL1 1926/4885ATM 4604/4885
US-20130032766-A1 METAL COMPLEXES COMPRISING DIAZABENZIMIDAZOLOCARBENE LIGANDS AND THE USE THEREOF IN OLEDS OCIAD1, OCIAD2, DRD2 KDM4E 4587/4885L3MBTL1 2826/4885ATM 3382/4885
US-20110253988-A1 BRIDGED BENZIMIDAZOLE-CARBENE COMPLEXES AND USE THEREOF IN OLEDS CCND1, DRD2, CCND2 KDM4E 3589/4885L3MBTL1 1507/4885ATM 3853/4885
US-11839140-B2 Metal complexes comprising diazabenzmidazolocarbene ligands and the use thereof in OLEDS OCIAD1, OCIAD2, DRD2 KDM4E 4573/4885L3MBTL1 2835/4885ATM 3351/4885
US-20170025626-A1 Metal Complexes Comprising Diazabenzmidazolocarbene Ligands and the Use Thereof in OLEDS OCIAD1, OCIAD2, DRD2 KDM4E 4573/4885L3MBTL1 2835/4885ATM 3351/4885
US-20200373503-A1 HETEROLEPTIC CARBENE COMPLEXES AND THE USE THEREOF IN ORGANIC ELECTRONICS OCIAD2, OCIAD1, CLTB KDM4E 3813/4885L3MBTL1 1656/4885ATM 4500/4885
US-11189806-B2 Heteroleptic carbene complexes and the use thereof in organic electronics OCIAD2, OCIAD1, CLTB KDM4E 3813/4885L3MBTL1 1656/4885ATM 4500/4885
US-20120012821-A1 SILYL- AND HETEROATOM-SUBSTITUTED COMPOUNDS SELECTED FROM CARBAZOLES, DIBENZOFURANS, DIBENZOTHIOPHENES AND DIBENZOPHOSPHOLES, AND USE THEREOF IN ORGANIC ELECTRONICS DDT, CDKL1, CDK2 KDM4E 2857/4885L3MBTL1 198/4885ATM 3045/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.