SCHEMBL9920640

SCHEMBL9920640

c1ccc(-c2ccccc2-c2cc(-c3cccc(-n4c5ccccc5c5ccccc54)c3)c3ccc4c(-c5ccccc5-c5ccccc5)cc(-c5ccccc5-c5ccccc5)c5ccc2c3c45)cc1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.46
KDM4E B2RXH2 1/20 0.46
ATM Q13315 1/20 0.46
MAPK14 Q16539 1/20 0.37
HSD17B10 Q99714 1/20 0.36
KMT2A Q03164 3/20 0.34
IL1R1 P14778 1/20 0.34
GRM5 P41594 1/20 0.34
MEN1 O00255 2/20 0.33
ALDH1A1 P00352 2/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
PDE10A Q9Y233 1/20 0.33
ASH1L Q9NR48 3/20 0.32
FOLH1 Q04609 1/20 0.31
GAA P10253 1/20 0.31
DUSP3 P51452 1/20 0.31
HTR6 P50406 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24295147 0.90 L3MBTL1 (0.57) L3MBTL1KDM4EATMMAPK14HSD17B10
SCHEMBL9920639 0.89 L3MBTL1 (0.49) L3MBTL1KDM4EATMMAPK14HSD17B10
SCHEMBL9920645 0.88 KDM4E (0.41) L3MBTL1KDM4EATMMAPK14HSD17B10
SCHEMBL12853965 0.87 L3MBTL1 (0.55) L3MBTL1KDM4EATMMAPK14HSD17B10
SCHEMBL64366 0.87 L3MBTL1 (0.55) L3MBTL1KDM4EATMMAPK14HSD17B10
SCHEMBL9921079 0.87 KDM4E (0.35) L3MBTL1KDM4EATMMAPK14HSD17B10
SCHEMBL9920790 0.86 L3MBTL1 (0.44) L3MBTL1KDM4EATMMAPK14HSD17B10
SCHEMBL9920964 0.86 L3MBTL1 (0.44) L3MBTL1KDM4EATMMAPK14HSD17B10
SCHEMBL9920794 0.86 KDM4E (0.44) L3MBTL1KDM4EATMMAPK14HSD17B10
SCHEMBL9920750 0.85 L3MBTL1 (0.42) L3MBTL1KDM4EATMMAPK14HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2463352-B1 Light emitting device material and light emitting device TORAY INDUSTRIES (JP) 2018-05-02 EP disclosed
US-20140061629-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2014-03-06 US disclosed
US-20140061629-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2014-03-06 US disclosed
EP-2463351-A2 Light emitting device material and light emitting device Toray Industries, Inc. (JP) 2012-06-13 EP disclosed
EP-2463352-A2 Light emitting device material and light emitting device Toray Industries, Inc. (JP) 2012-06-13 EP disclosed
US-20090096356-A1 Light-emitting device material and light-emitting device TORAY INDUSTRIES, INC. (JP) 2009-04-16 US disclosed
US-20090096356-A1 Light-emitting device material and light-emitting device TORAY INDUSTRIES, INC. (JP) 2009-04-16 US disclosed
EP-1942171-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2008-07-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090096356-A1 Light-emitting device material and light-emitting device PRMT9, CCNL2, MRPL9 L3MBTL1 283/4885KDM4E 2433/4885ATM 1983/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.