SCHEMBL9921071

SCHEMBL9921071

Cc1ccc(-c2cc(-c3cc(C)cc(-n4c5ccccc5c5ccccc54)c3)c3ccc4cc(C(C)(C)C)cc5ccc2c3c54)cc1

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.32
ALDH1A1 P00352 2/20 0.32
MAPK1 P28482 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
FLT3 P36888 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30
KDM4E B2RXH2 1/20 0.30
ATM Q13315 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9920778 0.92 ALDH1A1 (0.36) MAPTALDH1A1MAPK1NPSR1RXFP1
SCHEMBL9920782 0.92 ALDH1A1 (0.34) MAPTALDH1A1MAPK1NPSR1RXFP1
SCHEMBL9921090 0.92 ALDH1A1 (0.34) MAPTALDH1A1MAPK1NPSR1RXFP1
SCHEMBL9920916 0.91 ALDH1A1 (0.35) MAPTALDH1A1MAPK1NPSR1FLT3
SCHEMBL9920775 0.90 FLT3 (0.36) MAPTALDH1A1MAPK1NPSR1FLT3
SCHEMBL9920780 0.89 ALDH1A1 (0.34) MAPTALDH1A1MAPK1NPSR1RXFP1
SCHEMBL9921108 0.89 ALDH1A1 (0.34) MAPTALDH1A1MAPK1NPSR1RXFP1
SCHEMBL9920638 0.89 ALDH1A1 (0.34) MAPTALDH1A1MAPK1NPSR1RXFP1
SCHEMBL9920855 0.88 ALDH1A1 (0.34) MAPTALDH1A1MAPK1NPSR1RXFP1
SCHEMBL21234890 0.88 NPSR1 (0.35) MAPTALDH1A1MAPK1NPSR1RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2463352-B1 Light emitting device material and light emitting device TORAY INDUSTRIES (JP) 2018-05-02 EP disclosed
EP-1942171-B1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES (JP) 2018-04-18 EP disclosed
US-20140061629-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2014-03-06 US disclosed
US-20140061629-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2014-03-06 US disclosed
EP-2463352-A2 Light emitting device material and light emitting device Toray Industries, Inc. (JP) 2012-06-13 EP disclosed
EP-2463351-A2 Light emitting device material and light emitting device Toray Industries, Inc. (JP) 2012-06-13 EP disclosed
US-20090096356-A1 Light-emitting device material and light-emitting device TORAY INDUSTRIES, INC. (JP) 2009-04-16 US disclosed
US-20090096356-A1 Light-emitting device material and light-emitting device TORAY INDUSTRIES, INC. (JP) 2009-04-16 US disclosed
EP-1942171-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2008-07-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090096356-A1 Light-emitting device material and light-emitting device PRMT9, CCNL2, MRPL9 MAPT 3173/4885ALDH1A1 1929/4885MAPK1 1279/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.