Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.55 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | BRAF | P15056 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29944867 | 1.00 | HDAC8 (0.63) | HDAC8HDAC6ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL5909363 | 0.85 | HDAC8 (0.83) | HDAC8HDAC6ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8543766 | 0.85 | ALDH1A1 (0.55) | HDAC8HDAC6ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL9921285 | 0.83 | SMN1; SMN2 (0.59) | ALDH1A1KDM4ESMN1; SMN2NPSR1HSD17B10 | |
| SCHEMBL28308086 | 0.83 | SMN1; SMN2 (0.58) | HDAC8HDAC6ALDH1A1SMN1; SMN2PBRM1 | |
| SCHEMBL7188655 | 0.82 | SMN1; SMN2 (0.54) | HDAC8HDAC6ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL6999270 | 0.82 | PBRM1 (0.58) | ALDH1A1KDM4ESMN1; SMN2NPSR1HSD17B10 | |
| SCHEMBL6159659 | 0.82 | KDM4E (0.62) | HDAC8HDAC6ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL294944 | 0.82 | KDM4E (0.66) | ALDH1A1KDM4ESMN1; SMN2NPSR1HSD17B10 | |
| SCHEMBL31035124 | 0.82 | KDM4E (0.66) | ALDH1A1KDM4ESMN1; SMN2NPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 661 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119194842-A | Method for preparing uniform and compact carbon coating on surface of carbon fiber | 山东理工大学 | 2024-12-27 | — | — | CN | claimed |
| CN-111100225-B | Propylene polymerization method and device | 中国石油化工股份有限公司 | 2022-08-19 | — | — | CN | claimed |
| CN-114395129-A | Preparation method of polyether polyol with photodegradation characteristic | 山东一诺威新材料有限公司 | 2022-04-26 | — | — | CN | claimed |
| CN-109337282-B | High-thermal-stability polyformaldehyde resin and preparation method thereof | 万华化学集团股份有限公司 | 2021-03-09 | — | — | CN | claimed |
| CN-112127179-A | Low-temperature forebath scouring and dyeing enzyme treatment auxiliary agent | 清远瑞华助剂有限公司 | 2020-12-25 | — | — | CN | claimed |
| CN-108963389-B | Gelable system for lithium-air battery and preparation method and application thereof | 北京师范大学 | 2020-11-13 | — | — | CN | claimed |
| CN-111100225-A | Propylene polymerization method and device | 中国石油化工股份有限公司 | 2020-05-05 | — | — | CN | claimed |
| EP-3637525-A1 | FLEXIBLE ALL-SOLID-STATE LITHIUM-ION SECONDARY BATTERY AND MANUFACTURING METHOD THEREFOR | Beijing Normal University (CN) | 2020-04-15 | — | — | EP | claimed |
| EP-3637524-A1 | GELATINIZED SYSTEM AND APPLICATIONS IN LITHIUM AIR BATTERY, SUPER CAPACITOR OR CAPACITOR BATTERY IN ORGANIC SYSTEM | Beijing Normal University (CN) | 2020-04-15 | — | — | EP | claimed |
| US-20200099097-A1 | GELABLE SYSTEM AND USES THEREOF IN LITHIUM-AIR BATTERIES, ORGANIC SUPERCAPACITORS OR CAPACITOR BATTERIES | BEIJING NORMAL UNIVERSITY (CN) | 2020-03-26 | — | — | US | claimed |
| EP-1917246-B1 | BENZOQUINAZOLINE DERIVATIVES AND THEIR USE IN TREATING BONE DISORDERS | NOVARTIS AG (CH) | 2009-11-11 | — | — | EP | claimed |
| WO-2008122787-A1 | PIPERAZINE COMPOUNDS FOR THE INHIBITION OF HAEMATOPOIETIC PROSTAGLANDIN D SYNTHASE | EVOTEC AG (DE) | 2008-10-16 | — | — | WO | claimed |
| US-20080227782-A1 | PYRIMIDINE AMIDE COMPOUNDS AS PGDS INHIBITORS | AVENTIS PHARMACEUTICALS INC (US) | 2008-09-18 | — | — | US | claimed |
| EP-1937652-A1 | PYRIMIDINE AMIDE COMPOUNDS AS PGDS INHIBITORS | Aventis Pharmaceuticals Inc. (US) | 2008-07-02 | — | — | EP | claimed |
| EP-1917246-A1 | BENZOQUINAZOLINE DERIVATIVES AND THEIR USE IN TREATING BONE DISORDERS | Novartis AG (CH) | 2008-05-07 | — | — | EP | claimed |
| CN-100339442-C | Method for preparing organic pigment of red benzimidazolones | UNIV HUADONG TECHNOLOGY (CN) | 2007-09-26 | — | — | CN | claimed |
| WO-2007041634-A1 | PYRIMIDINE AMIDE COMPOUNDS AS PGDS INHIBITORS | AVENTIS PHARMACEUTICALS INC. (US) | 2007-04-12 | — | — | WO | claimed |
| WO-2007020046-A1 | BENZOQUINAZOLINE DERIVATIVES AND THEIR USE IN TREATING BONE DISORDERS | NOVARTIS AG (CH) | 2007-02-22 | — | — | WO | claimed |
| CN-1569968-A | Yellow, orange benzimidazolone like azo dye making method | UNIV EAST CHINA SCIENCE & TECH (CN) | 2005-01-26 | — | — | CN | claimed |
| CN-1563202-A | Method for preparing organic pigment of red benzimidazolones | UNIV HUADONG TECHNOLOGY (CN) | 2005-01-12 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227782-A1 | PYRIMIDINE AMIDE COMPOUNDS AS PGDS INHIBITORS | HRH2, HRH1, LTC4S | HDAC8 2170/4885HDAC6 1580/4885ALDH1A1 871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.