SCHEMBL9921486

SCHEMBL9921486

NC(=O)c1cccc(NNc2cccc(C(N)=O)c2)c1

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.61
KMT2A Q03164 1/20 0.61
PARP1 P09874 17/20 0.57
PARP10 Q53GL7 9/20 0.57
PARP15 Q460N3 5/20 0.57
PARP14 Q460N5 4/20 0.57
ROCK1 Q13464 1/20 0.51
POLB P06746 1/20 0.50
CYP3A4 P08684 1/20 0.50
MAPT P10636 1/20 0.50
TSHR P16473 1/20 0.50
CYP2C19 P33261 1/20 0.50
RECQL P46063 1/20 0.50
BLM P54132 1/20 0.50
PMP22 Q01453 1/20 0.50
HSD17B10 Q99714 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29490361 0.85 MEN1 (0.59) MEN1KMT2APARP1PARP10PARP15
SCHEMBL2475659 0.85 MEN1 (0.59) MEN1KMT2APARP1PARP10PARP15
SCHEMBL8722945 0.85 MEN1 (0.59) MEN1KMT2APARP1PARP10PARP15
SCHEMBL19091151 0.83 MEN1 (0.57) MEN1KMT2APARP1PARP10PARP15
SCHEMBL2850002 0.83 MEN1 (0.67) MEN1KMT2APARP1PARP10PARP15
SCHEMBL15387015 0.83 MEN1 (0.62) MEN1KMT2APARP1PARP10PARP15
SCHEMBL2566629 0.83 PARP1 (0.61) MEN1KMT2APARP1PARP10PARP15
SCHEMBL3094251 0.82 RHOA (0.57) MEN1KMT2APARP1PARP10PARP15
SCHEMBL4893340 0.82 PARP1 (0.66) MEN1KMT2APARP1PARP10PARP15
SCHEMBL5425792 0.82 MEN1 (0.65) MEN1KMT2APARP1PARP10PARP15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9169339-B2 Curable composition, molded product and method for producing molded product DAIKIN INDUSTRIES, LTD. (JP) 2015-10-27 US disclosed
US-9169339-B2 Curable composition, molded product and method for producing molded product DAIKIN INDUSTRIES, LTD. (JP) 2015-10-27 US disclosed
US-20130190456-A1 CURABLE COMPOSITION, MOLDED ARTICLE AND METHOD FOR PRODUCING MOLDED ARTICLE DAIKIN INDUSTRIES, LTD. (JP) 2013-07-25 US disclosed
US-20130190456-A1 CURABLE COMPOSITION, MOLDED ARTICLE AND METHOD FOR PRODUCING MOLDED ARTICLE DAIKIN INDUSTRIES, LTD. (JP) 2013-07-25 US disclosed
WO-2012077583-A1 CURABLE COMPOSITION, MOLDED PRODUCT AND METHOD FOR PRODUCING MOLDED PRODUCT DAIKIN INDUSTRIES, LTD. (JP) 2012-06-14 WO disclosed