Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | PARP1 | P09874 | 15/20 | 0.56 |
| ▸ | PARP10 | Q53GL7 | 9/20 | 0.56 |
| ▸ | PARP15 | Q460N3 | 5/20 | 0.56 |
| ▸ | PARP14 | Q460N5 | 4/20 | 0.56 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9921486 | 0.85 | MEN1 (0.61) | MEN1KMT2APARP1PARP10PARP15 | |
| SCHEMBL2475659 | 0.83 | MEN1 (0.59) | MEN1KMT2APARP1PARP10PARP15 | |
| SCHEMBL29490361 | 0.83 | MEN1 (0.59) | MEN1KMT2APARP1PARP10PARP15 | |
| SCHEMBL15387015 | 0.82 | MEN1 (0.62) | MEN1KMT2APARP1PARP10PARP15 | |
| SCHEMBL2566629 | 0.82 | PARP1 (0.61) | MEN1KMT2APARP1PARP10PARP15 | |
| SCHEMBL19091151 | 0.82 | MEN1 (0.57) | MEN1KMT2APARP1PARP10PARP15 | |
| SCHEMBL2850002 | 0.82 | MEN1 (0.67) | MEN1KMT2APARP1PARP10PARP15 | |
| SCHEMBL30727559 | 0.81 | AKR1C3 (0.58) | MEN1KMT2A | |
| SCHEMBL2039191 | 0.81 | AKR1C3 (0.58) | MEN1KMT2A | |
| SCHEMBL24934249 | 0.80 | ALDH1A1 (0.61) | MEN1KMT2APARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998045298-A1 | ANTIVIRAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 1998-10-15 | — | — | WO | disclosed |