SCHEMBL9921573

SCHEMBL9921573

c1ccc2c(c1)c1ccccc1c1nsnc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.39
KDM4E B2RXH2 4/20 0.39
HSD17B10 Q99714 2/20 0.39
HIF1A Q16665 1/20 0.39
LMNA P02545 3/20 0.37
ALDH1A1 P00352 4/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
GPR3 P46089 3/20 0.35
HPRT1 P00492 1/20 0.35
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
HPGD P15428 2/20 0.33
GLA P06280 1/20 0.33
GAA P10253 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
TXNRD1 Q16881 1/20 0.33
TXNRD3 Q86VQ6 1/20 0.33
TXNRD2 Q9NNW7 1/20 0.33
TDP2 O95551 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15298698 0.81 DCLK1 (0.39) MAPTALDH1A1MEN1KMT2AHPGD
SCHEMBL23145180 0.79 L3MBTL1 (0.54) MAPTKDM4EHIF1ALMNAALDH1A1
SCHEMBL15298674 0.78 JAK2 (0.34) MAPTKDM4EHSD17B10HIF1AMEN1
SCHEMBL15298671 0.78 JAK2 (0.34) MAPTKDM4EHSD17B10HIF1AMEN1
SCHEMBL9921575 0.77 KIF11 (0.45) HSD17B10ALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL13387379 0.76 MAPT (0.35) MAPTKDM4EHSD17B10HIF1AALDH1A1
SCHEMBL12587613 0.76 L3MBTL1 (0.39) MAPTKDM4EHSD17B10HIF1AALDH1A1
SCHEMBL15298664 0.75 JAK2 (0.39) MEN1KMT2A
SCHEMBL15298669 0.75 JAK2 (0.39) MEN1KMT2A
SCHEMBL14701343 0.75 ESR1 (0.36) MAPTKDM4EHSD17B10HIF1ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220389310-A1 LUMINESCENT MATERIALS AND METHODS THEREOF UNIVERSITY OF WASHINGTON (US) 2022-12-08 US claimed
WO-2021062035-A1 LUMINESCENT MATERIALS AND METHODS THEREOF UNIVERSITY OF WASHINGTON (US) 2021-04-01 WO claimed
US-20220389310-A1 LUMINESCENT MATERIALS AND METHODS THEREOF UNIVERSITY OF WASHINGTON (US) 2022-12-08 US disclosed
WO-2021062035-A1 LUMINESCENT MATERIALS AND METHODS THEREOF UNIVERSITY OF WASHINGTON (US) 2021-04-01 WO disclosed
US-20130256647-A1 NOVEL ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING SAME CANON KABUSHIKI KAISHA (JP) 2013-10-03 US disclosed
US-20130256647-A1 NOVEL ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING SAME CANON KABUSHIKI KAISHA (JP) 2013-10-03 US disclosed
WO-2012077478-A1 NOVEL ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING SAME CANON KABUSHIKI KAISHA (JP) 2012-06-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220389310-A1 LUMINESCENT MATERIALS AND METHODS THEREOF TYR, GSTA2, CYBA MAPT 2034/4885KDM4E 3167/4885HSD17B10 3261/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.