Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12798874 | 0.91 | TDP1 (0.62) | TDP1ALDH1A1CYP3A4ALOX15MAPT | |
| SCHEMBL9820329 | 0.86 | TDP1 (0.61) | TDP1ALDH1A1CYP3A4ALOX15MAPT | |
| SCHEMBL11295679 | 0.86 | TDP1 (0.56) | TDP1ALDH1A1CYP3A4ALOX15MAPT | |
| SCHEMBL31423774 | 0.85 | TDP1 (0.60) | TDP1ALDH1A1CYP3A4ALOX15MAPT | |
| SCHEMBL11079242 | 0.85 | TDP1 (0.60) | TDP1ALDH1A1CYP3A4ALOX15MAPT | |
| SCHEMBL5952783 | 0.84 | TSHR (0.56) | TDP1ALDH1A1CYP3A4ALOX15MAPT | |
| SCHEMBL4719966 | 0.84 | TSHR (0.58) | TDP1ALDH1A1CYP3A4ALOX15MAPT | |
| SCHEMBL27947665 | 0.84 | TDP1 (0.55) | TDP1ALDH1A1CYP3A4ALOX15MAPT | |
| Hydrochloric Acid SCHEMBL7368798 | 0.84 | TDP1 (0.58) | TDP1ALDH1A1CYP3A4ALOX15MAPT | |
| SCHEMBL30989211 | 0.83 | TDP1 (0.62) | TDP1ALDH1A1CYP3A4ALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014133526-A1 | COLORED PIGMENT PARTICLES FOR ELECTROPHORETIC DISPLAYS | EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) | 2014-09-04 | — | — | WO | claimed |
| EP-3441389-B1 | PYRAZOLE-OXAZOLIDINONE COMPOUND FOR ANTI-HEPATITIS B VIRUS | SHANGHAI ZHIMENG BIOPHARMA INC (CN) | 2021-09-08 | — | — | EP | disclosed |
| CN-109311865-B | Pyrazole-oxazolidinone compound for resisting hepatitis B virus | 上海挚盟医药科技有限公司 | 2021-08-31 | — | — | CN | disclosed |
| US-20190152963-A1 | PYRAZOLE-OXAZOLIDINONE COMPOUND FOR ANTI-HEPATITIS B VIRUS | SHANGHAI ZHIMENG BIOPHARMA, INC. (CN) | 2019-05-23 | — | — | US | disclosed |
| EP-3441389-A1 | PYRAZOLE-OXAZOLIDINONE COMPOUND FOR ANTI-HEPATITIS B VIRUS | Shanghai Zhimeng Biopharma Co., Ltd (CN) | 2019-02-13 | — | — | EP | disclosed |
| CN-109311865-A | Pyrazole-oxazolidinone compound for resisting hepatitis B virus | 上海挚盟医药科技有限公司 | 2019-02-05 | — | — | CN | disclosed |
| US-9846345-B2 | Colored pigment particles for electrophoretic displays | EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) | 2017-12-19 | — | — | US | disclosed |
| US-20160018716-A1 | COLORED PIGMENT PARTICLES FOR ELECTROPHORETIC DISPLAYS | CRESTLINE DIRECT FINANCE, L.P. | 2016-01-21 | — | — | US | disclosed |
| EP-2454253-B1 | AMINOPYRIDINE DERIVATIVES FOR TREATING TUMORS AND INFLAMMATORY DISEASES | MERCK PATENT GMBH (DE) | 2015-01-21 | — | — | EP | disclosed |
| WO-2014133526-A1 | COLORED PIGMENT PARTICLES FOR ELECTROPHORETIC DISPLAYS | EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) | 2014-09-04 | — | — | WO | disclosed |
| CN-102471317-B | Aminopyridine derivatives for treating tumors and inflammatory diseases | MERCK PATENT GMBH | 2014-02-26 | — | — | CN | disclosed |
| US-8648201-B2 | Aminopyridine derivatives for treating tumors and inflammatory diseases | MERCK PATENT GMBH (DE) | 2014-02-11 | — | — | US | disclosed |
| US-8648201-B2 | Aminopyridine derivatives for treating tumors and inflammatory diseases | MERCK PATENT GMBH (DE) | 2014-02-11 | — | — | US | disclosed |
| EP-2454253-A1 | AMINOPYRIDINE DERIVATIVES FOR TREATING TUMORS AND INFLAMMATORY DISEASES | Merck Patent GmbH (DE) | 2012-05-23 | — | — | EP | disclosed |
| CN-102471317-A | Aminopyridine derivatives for treating tumors and inflammatory diseases | MERCK PATENT GMBH | 2012-05-23 | — | — | CN | disclosed |
| US-20120115861-A1 | AMINOPYRIDINE DERIVATIVES FOR TREATING TUMORS AND INFLAMMATORY DISEASES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-05-10 | — | — | US | disclosed |
| US-20120115861-A1 | AMINOPYRIDINE DERIVATIVES FOR TREATING TUMORS AND INFLAMMATORY DISEASES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-05-10 | — | — | US | disclosed |
| WO-2011006567-A1 | AMINOPYRIDINE DERIVATIVES FOR TREATING TUMORS AND INFLAMMATORY DISEASES | MERCK PATENT GMBH (DE) | 2011-01-20 | — | — | WO | disclosed |
| US-20070191444-A1 | Benzimidazolyl derivatives | MERCK PATENT GMBH (DE) | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191444-A1 | Benzimidazolyl derivatives | JAK1, MARK1, RAF1 | TDP1 1372/4885ALDH1A1 1382/4885CYP3A4 1881/4885 |
| US-20190152963-A1 | PYRAZOLE-OXAZOLIDINONE COMPOUND FOR ANTI-HEPATITIS B VIRUS | HAVCR2, ZC3HAV1, ZC3HAV1L | TDP1 4457/4885ALDH1A1 795/4885CYP3A4 16/4885 |
| US-20120115861-A1 | AMINOPYRIDINE DERIVATIVES FOR TREATING TUMORS AND INFLAMMATORY DISEASES | PDK1, PDK2, PDK4 | TDP1 639/4885ALDH1A1 1341/4885CYP3A4 2520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.