Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.43 |
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14706285 | 1.00 | MAOA (0.43) | MAOAMAOBACHEATMKDM4E | |
| SCHEMBL14706283 | 0.99 | MAOA (0.43) | MAOAMAOBACHEATMKDM4E | |
| SCHEMBL9921806 | 0.99 | MAOA (0.43) | MAOAMAOBACHEATMKDM4E | |
| SCHEMBL12919325 | 0.97 | MAOA (0.43) | MAOAMAOBACHEATMKDM4E | |
| SCHEMBL12919280 | 0.96 | MAOA (0.40) | MAOAMAOBACHEATMKDM4E | |
| SCHEMBL12919260 | 0.95 | KDM4E (0.40) | MAOAMAOBACHEATMKDM4E | |
| SCHEMBL5944378 | 0.94 | MAOA (0.39) | MAOAMAOBACHEATMKDM4E | |
| SCHEMBL14706284 | 0.94 | KDM4E (0.41) | MAOAMAOBACHEATMKDM4E | |
| SCHEMBL12919324 | 0.94 | KDM4E (0.41) | MAOAMAOBACHEATMKDM4E | |
| SCHEMBL9921821 | 0.93 | CYP17A1 (0.41) | MAOAMAOBACHEATMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8377573-B2 | Compound having substituted pyridyl group and pyridoindole ring structure linked through phenylene group, and organic electroluminescent device | HODOGAYA CHEMICAL CO., LTD. (JP) | 2013-02-19 | — | — | US | disclosed |
| US-8377573-B2 | Compound having substituted pyridyl group and pyridoindole ring structure linked through phenylene group, and organic electroluminescent device | HODOGAYA CHEMICAL CO., LTD. (JP) | 2013-02-19 | — | — | US | disclosed |
| EP-2463288-A1 | Compound having substituted pyridyl group and pyridoindole ring structure linked through phenylene group, and organic electroluminescent device | Hodogaya Chemical Co., Ltd. (JP) | 2012-06-13 | — | — | EP | disclosed |
| US-20110006291-A1 | COMPOUND HAVING SUBSTITUTED PYRIDYL GROUP AND PYRIDOINDOLE RING STRUCTURE LINKED THROUGH PHENYLENE GROUP, AND ORGANIC ELECTROLUMINESCENT DEVICE | HODOGAYA CHEMICAL CO. LTD. (JP) | 2011-01-13 | — | — | US | disclosed |
| US-20110006291-A1 | COMPOUND HAVING SUBSTITUTED PYRIDYL GROUP AND PYRIDOINDOLE RING STRUCTURE LINKED THROUGH PHENYLENE GROUP, AND ORGANIC ELECTROLUMINESCENT DEVICE | HODOGAYA CHEMICAL CO. LTD. (JP) | 2011-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110006291-A1 | COMPOUND HAVING SUBSTITUTED PYRIDYL GROUP AND PYRIDOINDOLE RING STRUCTURE LINKED THROUGH PHENYLENE GROUP, AND ORGANIC ELECTROLUMINESCENT DEVICE | KCNH3, KCNH2, CHRNA9 | MAOA 599/4885MAOB 360/4885ACHE 1227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.