Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | ESRRA | P11474 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12161531 | 0.93 | P2RY12 (0.41) | P2RY12IMPDH2LMNATP53MEN1 | |
| SCHEMBL12177337 | 0.92 | P2RY12 (0.37) | P2RY12IMPDH2LMNATP53CA12 | |
| SCHEMBL9922470 | 0.89 | P2RY12 (0.51) | P2RY12IMPDH2LMNAMEN1KMT2A | |
| SCHEMBL9923020 | 0.88 | P2RY12 (0.41) | P2RY12IMPDH2LMNATP53MEN1 | |
| SCHEMBL9922975 | 0.88 | P2RY12 (0.42) | P2RY12LMNATP53KDM4EMAPT | |
| SCHEMBL9922151 | 0.86 | P2RY12 (0.41) | P2RY12LMNAKDM4EMAPTHTT | |
| SCHEMBL9922152 | 0.86 | P2RY12 (0.41) | P2RY12LMNATP53KDM4EMAPT | |
| SCHEMBL9922785 | 0.85 | ESRRA (0.42) | P2RY12LMNATP53KDM4EMAPT | |
| SCHEMBL9922970 | 0.84 | P2RY12 (0.40) | P2RY12TP53CA12CA1CA9 | |
| SCHEMBL9922777 | 0.83 | P2RY12 (0.40) | P2RY12IMPDH2LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149688-A1 | PLATELET ADP RECEPTOR INHIBITORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149688-A1 | PLATELET ADP RECEPTOR INHIBITORS | TBXA2R, GP6, P2RY6 | P2RY12 18/4885IMPDH2 3419/4885LMNA 3603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.