Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.30 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12161540 | 0.93 | P2RY12 (0.40) | P2RY12MAPK8KCNH2 | |
| SCHEMBL14228363 | 0.92 | P2RY12 (0.36) | P2RY12MAPK8CA12CA1CA9 | |
| SCHEMBL9922466 | 0.89 | P2RY12 (0.49) | P2RY12MAPK8KCNH2 | |
| SCHEMBL12177188 | 0.89 | P2RY12 (0.40) | P2RY12MAPK8CA12CA9PPARG | |
| SCHEMBL9922152 | 0.86 | P2RY12 (0.41) | P2RY12CA12CA1CA9TP53 | |
| SCHEMBL9922975 | 0.86 | P2RY12 (0.42) | P2RY12CA12CA1CA9TP53 | |
| SCHEMBL9922974 | 0.85 | MAPT (0.39) | P2RY12CA1CA9TP53CA2 | |
| SCHEMBL9922151 | 0.85 | P2RY12 (0.41) | P2RY12CA12CA1CA9CA2 | |
| SCHEMBL9922150 | 0.84 | P2RY12 (0.41) | P2RY12CA12CA1CA9TP53 | |
| SCHEMBL9922785 | 0.83 | ESRRA (0.42) | P2RY12MAPK8CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149688-A1 | PLATELET ADP RECEPTOR INHIBITORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149688-A1 | PLATELET ADP RECEPTOR INHIBITORS | TBXA2R, GP6, P2RY6 | P2RY12 18/4885MAPK8 1550/4885CA12 4616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.