Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8931764 | 0.91 | AR (0.34) | ARRORCEPHX2NR1H4 | |
| SCHEMBL540222 | 0.82 | AR (0.36) | AREPHX2NR1H4 | |
| SCHEMBL540031 | 0.81 | AR (0.36) | AREPHX2NR1H4 | |
| SCHEMBL539828 | 0.80 | EPHX2 (0.43) | EPHX2NR1H4 | |
| SCHEMBL15465958 | 0.77 | EPHX2 (0.42) | EPHX2NR1H4 | |
| SCHEMBL794053 | 0.74 | KCNH2 (0.44) | EPHX2NR1H4 | |
| SCHEMBL540353 | 0.74 | AR (0.31) | AR | |
| SCHEMBL540749 | 0.74 | EPHX2 (0.37) | EPHX2NR1H4 | |
| SCHEMBL539934 | 0.73 | AR (0.31) | AR | |
| SCHEMBL2306565 | 0.73 | FAAH (0.33) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2463265-A2 | Process for the preparation of insecticidal aryl pyrrolidines | Bayer CropScience AG (DE) | 2012-06-13 | — | — | EP | disclosed |