Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 8/20 | 0.34 |
| ▸ | RORC | P51449 | 3/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | TACR3 | P29371 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9922359 | 0.91 | AR (0.33) | ARRORCEPHX2NR1H4 | |
| SCHEMBL539828 | 0.84 | EPHX2 (0.43) | EPHX2NR1H4ENPP2NOTUM | |
| SCHEMBL540222 | 0.82 | AR (0.36) | AREPHX2NR1H4 | |
| SCHEMBL540031 | 0.81 | AR (0.36) | AREPHX2NR1H4 | |
| SCHEMBL15465958 | 0.80 | EPHX2 (0.42) | EPHX2NR1H4ENPP2 | |
| SCHEMBL794053 | 0.78 | KCNH2 (0.44) | EPHX2NR1H4 | |
| SCHEMBL540749 | 0.77 | EPHX2 (0.37) | EPHX2NR1H4NOTUM | |
| SCHEMBL15468119 | 0.77 | TRPV1 (0.38) | EPHX2NR1H4ENPP2 | |
| SCHEMBL793911 | 0.77 | EPHX2 (0.36) | EPHX2NR1H4ENPP2NOTUM | |
| SCHEMBL27971400 | 0.77 | ACLY (0.36) | ARENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150152086-A1 | Insecticidal Aryl Pyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-04 | — | — | US | disclosed |
| US-20150152086-A1 | Insecticidal Aryl Pyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-04 | — | — | US | disclosed |
| US-8980937-B2 | Insecticidal aryl pyrrolidines | BAYER CROPSCIENCE AG (DE) | 2015-03-17 | — | — | US | disclosed |
| US-8980937-B2 | Insecticidal aryl pyrrolidines | BAYER CROPSCIENCE AG (DE) | 2015-03-17 | — | — | US | disclosed |
| US-20120232278-A1 | Insecticidal Aryl Pyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-09-13 | — | — | US | disclosed |
| US-20120232278-A1 | Insecticidal Aryl Pyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-09-13 | — | — | US | disclosed |
| US-8188122-B2 | Insecticidal aryl pyrrolidines | BAYER CROPSCIENCE AG (DE) | 2012-05-29 | — | — | US | disclosed |
| US-8188122-B2 | Insecticidal aryl pyrrolidines | BAYER CROPSCIENCE AG (DE) | 2012-05-29 | — | — | US | disclosed |
| US-20110082175-A1 | INSECTICIDAL ARYL PYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2011-04-07 | — | — | US | disclosed |
| US-20110082175-A1 | INSECTICIDAL ARYL PYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2011-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120232278-A1 | Insecticidal Aryl Pyrrolidines | DDT, ITPR3, CYP51A1 | AR 4257/4885RORC 2320/4885EPHX2 1114/4885 |
| US-20150152086-A1 | Insecticidal Aryl Pyrrolidines | DDT, ITPR3, CYP51A1 | AR 4257/4885RORC 2320/4885EPHX2 1114/4885 |
| US-20110082175-A1 | INSECTICIDAL ARYL PYRROLIDINES | DDT, ITPR3, CYP51A1 | AR 4257/4885RORC 2320/4885EPHX2 1114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.