Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | QPCT | Q16769 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | FLT1 | P17948 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.31 |
| ▸ | TEK | Q02763 | 1/20 | 0.31 |
| ▸ | KHK | P50053 | 1/20 | 0.30 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177235 | 0.93 | P2RY12 (0.37) | P2RY12QPCTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13182767 | 0.91 | P2RY12 (0.39) | P2RY12QPCTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12177273 | 0.90 | P2RY12 (0.37) | P2RY12QPCTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14113533 | 0.88 | P2RY12 (0.39) | P2RY12QPCTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14113530 | 0.86 | P2RY12 (0.35) | P2RY12QPCTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12161004 | 0.85 | P2RY12 (0.43) | P2RY12QPCTSMN1; SMN2KITEPHX1 | |
| SCHEMBL9922620 | 0.84 | CHRM5 (0.33) | P2RY12NPC1RAB9ASMN1; SMN2BRD4 | |
| SCHEMBL13638697 | 0.83 | P2RY12 (0.35) | P2RY12QPCTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9922077 | 0.82 | P2RY12 (0.47) | P2RY12QPCTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9922428 | 0.82 | P2RY12 (0.43) | P2RY12QPCTSMN1; SMN2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149688-A1 | PLATELET ADP RECEPTOR INHIBITORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149688-A1 | PLATELET ADP RECEPTOR INHIBITORS | TBXA2R, GP6, P2RY6 | P2RY12 18/4885QPCT 3147/4885NPC1 3099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.