Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.46 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | PYGL | P06737 | 8/20 | 0.40 |
| ▸ | PYGM | P11217 | 6/20 | 0.40 |
| ▸ | GUSB | P08236 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.39 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL990736 | 0.84 | GRM5 (0.46) | GRM5 | |
| SCHEMBL990757 | 0.84 | GRM5 (0.46) | GRM5 | |
| SCHEMBL2818567 | 0.84 | L3MBTL1 (0.47) | GRM5 | |
| SCHEMBL990345 | 0.83 | GRM5 (0.43) | GRM5 | |
| SCHEMBL990340 | 0.80 | L3MBTL1 (0.59) | GRM5 | |
| SCHEMBL992650 | 0.80 | NPC1 (0.45) | GRM5CNR2 | |
| SCHEMBL990862 | 0.80 | NPC1 (0.45) | GRM5CNR2 | |
| SCHEMBL2815651 | 0.79 | GRM5 (0.46) | GRM5 | |
| SCHEMBL1907158 | 0.79 | GRM5 (0.46) | GRM5 | |
| SCHEMBL990822 | 0.79 | NPC1 (0.48) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2272509-A1 | New Uses of metabotropic glutamate receptors | Novartis AG (CH) | 2011-01-12 | — | — | EP | disclosed |