Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9923510 | 0.84 | PTGER1 (0.45) | GCKLRRK2RAB9ANPC1SGMS2 | |
| SCHEMBL643874 | 0.80 | GCK (0.44) | GCKKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL12398724 | 0.72 | CXCR2 (0.76) | GCKKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL643296 | 0.69 | GCK (0.60) | GCKKMT2AMEN1CXCR2 | |
| SCHEMBL3529609 | 0.69 | KDM4E (0.72) | KMT2AALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL642139 | 0.69 | GCK (0.52) | GCKKMT2AMEN1RAB9ACXCR2 | |
| SCHEMBL22607251 | 0.67 | RAB9A (0.59) | KMT2AMEN1ALDH1A1RAB9ANPC1 | |
| SCHEMBL643713 | 0.66 | GCK (0.46) | GCKKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL18027718 | 0.66 | MEN1 (0.60) | KMT2AMEN1LRRK2RAB9ANPC1 | |
| SCHEMBL10253546 | 0.66 | GCK (0.46) | GCKKMT2AALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2463283-A1 | Fused phenyl Amido heterocyclic compounds for the prevention and treatment of glucokinase-mediated diseases | Pfizer Products Inc. (US) | 2012-06-13 | — | — | EP | disclosed |