Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 6/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL998164 | 0.73 | ROCK1 (0.37) | — | |
| SCHEMBL978875 | 0.70 | HCAR2 (0.35) | — | |
| SCHEMBL992382 | 0.69 | RAD52 (0.33) | P2RX7 | |
| SCHEMBL15409725 | 0.67 | P2RX7 (0.40) | P2RX7 | |
| SCHEMBL980672 | 0.63 | PTGIR (0.35) | — | |
| SCHEMBL15153028 | 0.62 | HCAR2 (0.32) | — | |
| SCHEMBL979099 | 0.61 | NPSR1 (0.35) | — | |
| SCHEMBL986289 | 0.60 | HDAC6 (0.43) | — | |
| SCHEMBL977783 | 0.57 | S1PR3 (0.33) | — | |
| SCHEMBL15153083 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011008709-A1 | APOPTOSIS SIGNAL-REGULATING KINASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2011-01-20 | — | — | WO | claimed |