Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 17/20 | 0.38 |
| ▸ | HTR2B | P41595 | 13/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 9/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9923998 | 0.88 | XIAP (0.40) | ALDH1A1POLBKMT2AHTR2CHTR2B | |
| SCHEMBL17188997 | 0.88 | XIAP (0.40) | ALDH1A1POLBKMT2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL23927083 | 0.86 | HTR2C (0.39) | ALDH1A1HTR2CHTR2BHTR2ANPC1 | |
| SCHEMBL1981450 | 0.83 | AAK1 (0.38) | ALDH1A1POLBKMT2AHTR2CHTR2B | |
| SCHEMBL9904768 | 0.81 | HTR2C (0.36) | ALDH1A1HTR2CHTR2BHTR2ARAB9A | |
| SCHEMBL1979639 | 0.81 | RAB9A (0.37) | ALDH1A1KMT2AHTR2CHTR2BHTR2A | |
| SCHEMBL29438022 | 0.80 | CA12 (0.39) | KMT2A | |
| SCHEMBL13721128 | 0.80 | ALDH1A1 (0.34) | ALDH1A1POLBKMT2AHTR2CHTR2B | |
| SCHEMBL9923816 | 0.80 | CA12 (0.39) | KMT2A | |
| SCHEMBL31157906 | 0.79 | KMT2A (0.40) | POLBKMT2AHTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012076877-A1 | HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS | AUTIFONY THERAPEUTICS LIMITED (GB) | 2012-06-14 | — | — | WO | disclosed |