SCHEMBL9924202

SCHEMBL9924202

CCC(O)CNC(Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.61
ACE P12821 3/20 0.60
SMN1; SMN2 Q16637 1/20 0.59
ITGB2 P05107 4/20 0.57
ICAM1 P05362 4/20 0.57
ITGAL P20701 4/20 0.57
KDM4E B2RXH2 2/20 0.57
APAF1 O14727 1/20 0.57
POLB P06746 1/20 0.57
MAPT P10636 1/20 0.57
RECQL P46063 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
ECE1 P42892 3/20 0.55
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
MMP2 P08253 1/20 0.55
MMP9 P14780 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30574989 0.89 ALOX15 (0.62) ALOX15ACESMN1; SMN2ITGB2ICAM1
SCHEMBL29072460 0.89 ALOX15 (0.62) ALOX15ACESMN1; SMN2ITGB2ICAM1
SCHEMBL6010110 0.89 SMN1; SMN2 (0.60) ALOX15ACESMN1; SMN2ITGB2ICAM1
SCHEMBL29072461 0.89 ALOX15 (0.62) ALOX15ACESMN1; SMN2ITGB2ICAM1
SCHEMBL29072471 0.89 ALOX15 (0.62) ALOX15ACESMN1; SMN2ITGB2ICAM1
SCHEMBL30575013 0.89 ALOX15 (0.62) ALOX15ACESMN1; SMN2ITGB2ICAM1
SCHEMBL6010119 0.89 SMN1; SMN2 (0.60) ALOX15ACESMN1; SMN2ITGB2ICAM1
Hydrochloric Acid SCHEMBL6010121 0.88 SMN1; SMN2 (0.59) ALOX15ACESMN1; SMN2ITGB2ICAM1
Hydrochloric Acid SCHEMBL6010113 0.88 SMN1; SMN2 (0.59) ALOX15ACESMN1; SMN2ITGB2ICAM1
SCHEMBL11589471 0.88 ACE (0.65) ALOX15ACESMN1; SMN2ITGB2ICAM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9204644-B2 Nanoparticles compositions containing polymers and anthranilic acid diamide insecticides for propagule coating E I DU PONT DE NEMOURS AND COMPANY (US) 2015-12-08 US disclosed
US-20150296781-A1 ACRYLATE/METHACRYLATE-BASED TRIBLOCK COPOLYMER/ANTHRANILIC DIAMIDE COMPOSITIONS FOR PROPAGULE COATING E. I. DUPONT DE NEMOURS AND COMPANY 2015-10-22 US disclosed
US-20140357483-A1 NANOPARTICLES COMPOSITIONS CONTAINING POLYMERS AND ANTHRANILIC ACID DIAMIDE INSECTICIDES FOR PROPAGULE COATING CORTEVA AGRISCIENCE LLC 2014-12-04 US disclosed
US-8575065-B2 Acrylate/methacrylate-based star copolymer/anthranilic diamide compositions for propagle coating E I DU PONT DE NEMOURS AND COMPANY (US) 2013-11-05 US disclosed
US-8569268-B2 Acrylate/methacrylate-based diblock copolymer/anthranilic diamide compositions for propagule coating E I DU PONT DE NEMOURS AND COMPANY (US) 2013-10-29 US disclosed
US-20120149567-A1 ACRYLATE/METHACRYLATE-BASED STAR COPOLYMER/ANTHRANILIC DIAMIDE COMPOSITIONS FOR PROPAGLE COATING E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-06-14 US disclosed
US-20120149566-A1 ACRYLATE/METHACRYLATE-BASED DIBLOCK COPOLYMER/ANTHRANILIC DIAMIDE COMPOSITIONS FOR PROPAGULE COATING E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150296781-A1 ACRYLATE/METHACRYLATE-BASED TRIBLOCK COPOLYMER/ANTHRANILIC DIAMIDE COMPOSITIONS FOR PROPAGULE COATING DDT, MTDH, API5 ALOX15 235/4885ACE 3979/4885SMN1; SMN2 3995/4885
US-20120149566-A1 ACRYLATE/METHACRYLATE-BASED DIBLOCK COPOLYMER/ANTHRANILIC DIAMIDE COMPOSITIONS FOR PROPAGULE COATING DDT, APMAP, MTDH ALOX15 191/4885ACE 3939/4885SMN1; SMN2 3910/4885
US-20120149567-A1 ACRYLATE/METHACRYLATE-BASED STAR COPOLYMER/ANTHRANILIC DIAMIDE COMPOSITIONS FOR PROPAGLE COATING STAMBP, MTDH, AGPS ALOX15 897/4885ACE 4224/4885SMN1; SMN2 3916/4885
US-20140357483-A1 NANOPARTICLES COMPOSITIONS CONTAINING POLYMERS AND ANTHRANILIC ACID DIAMIDE INSECTICIDES FOR PROPAGULE COATING MTDH, DDT, AGPS ALOX15 170/4885ACE 4283/4885SMN1; SMN2 3225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.