Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 8/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 5/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9924233 | 0.86 | KMT2A (0.49) | MCHR1KCNQ3KCNQ2PDE4BPDE4D | |
| SCHEMBL9924422 | 0.86 | KCNQ3 (0.42) | MCHR1KCNQ3KCNQ2ADRA2AADRA1A | |
| SCHEMBL9924284 | 0.85 | MCHR1 (0.41) | MCHR1KCNQ3KCNQ2PDE4BPDE4D | |
| SCHEMBL9924419 | 0.83 | KCNQ3 (0.41) | MCHR1KCNQ3KCNQ2PDE4BPDE4D | |
| SCHEMBL9900854 | 0.83 | KCNQ3 (0.41) | MCHR1KCNQ3KCNQ2PDE4BPDE4D | |
| SCHEMBL9901952 | 0.83 | KCNQ3 (0.41) | MCHR1KCNQ3KCNQ2PDE4BPDE4D | |
| SCHEMBL9900852 | 0.83 | KCNQ3 (0.41) | MCHR1KCNQ3KCNQ2PDE4BPDE4D | |
| SCHEMBL17206691 | 0.83 | KCNQ3 (0.41) | MCHR1KCNQ3KCNQ2PDE4BPDE4D | |
| SCHEMBL9924073 | 0.82 | MCHR1 (0.46) | MCHR1KCNQ3KCNQ2PDE4BPDE4D | |
| SCHEMBL9924232 | 0.82 | ALDH1A1 (0.39) | MCHR1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9169199-B2 | Cycloalkyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2015-10-27 | — | — | US | disclosed |
| WO-2012078867-A2 | CYCLOALKYL GUANIDINE F1F0-ATPASE INHIBITORS AND THERAPEUTIC USES THEREOF | LYCERA CORPORATION (US) | 2012-06-14 | — | — | WO | disclosed |