Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR3 | P32745 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9924269 | 0.94 | SSTR3 (0.45) | SSTR3MCHR1P2RX7SIGMAR1MAPK14 | |
| SCHEMBL9924242 | 0.94 | LMNA (0.40) | SSTR3MCHR1POLBLMNAALDH1A1 | |
| SCHEMBL9924268 | 0.93 | SSTR3 (0.46) | SSTR3MCHR1KCNH2PPARGALDH1A1 | |
| SCHEMBL9924426 | 0.93 | EPHX1 (0.44) | SSTR3MCHR1POLBLMNAKCNH2 | |
| SCHEMBL9924239 | 0.92 | MAPK14 (0.36) | SSTR3MCHR1P2RX7MAPK14DPP4 | |
| SCHEMBL9924429 | 0.91 | NTRK1 (0.43) | SIGMAR1ROCK2KDM1AALDH1A1 | |
| SCHEMBL17206626 | 0.90 | LMNA (0.42) | MCHR1P2RX7MAPK14LMNAKDM1A | |
| SCHEMBL9924428 | 0.88 | SMYD3 (0.46) | P2RX7SIGMAR1MAPK14POLBLMNA | |
| SCHEMBL9924237 | 0.86 | SIGMAR1 (0.39) | MCHR1SIGMAR1MAPK14ROCK2ROCK1 | |
| SCHEMBL17206627 | 0.86 | KMT2A (0.42) | SSTR3MCHR1SIGMAR1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9169199-B2 | Cycloalkyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2015-10-27 | — | — | US | disclosed |
| US-9169199-B2 | Cycloalkyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2015-10-27 | — | — | US | disclosed |
| WO-2012078867-A2 | CYCLOALKYL GUANIDINE F1F0-ATPASE INHIBITORS AND THERAPEUTIC USES THEREOF | LYCERA CORPORATION (US) | 2012-06-14 | — | — | WO | disclosed |