Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4146675 | 0.85 | MAPT (0.33) | GAAMAPTEPHX1 | |
| SCHEMBL8656113 | 0.80 | EPHX1 (0.31) | MAPTEPHX1 | |
| SCHEMBL4058588 | 0.69 | MAPT (0.41) | GAAMAPT | |
| SCHEMBL8197993 | 0.69 | MAPT (0.37) | GAAMAPT | |
| SCHEMBL8799466 | 0.69 | GAA (0.43) | GAAMAPT | |
| SCHEMBL4915107 | 0.66 | GAA (0.37) | GAAMAPT | |
| SCHEMBL15865155 | 0.66 | MAPT (0.37) | GAAMAPT | |
| SCHEMBL5412235 | 0.66 | GAA (0.37) | GAAMAPT | |
| SCHEMBL8900868 | 0.66 | GAA (0.38) | GAAMAPT | |
| SCHEMBL11710279 | 0.66 | GAA (0.43) | GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448961-A2 | TARGETS FOR RETROVIRUS ASSOCIATED DISEASES | Université de Liège (BE) | 2012-05-09 | — | — | EP | disclosed |
| US-20120090043-A1 | TARGETS FOR RETROVIRUS ASSOCIATED DISEASES | UNIVERSITE DE LIEGE (BE) | 2012-04-12 | — | — | US | disclosed |
| WO-2011000860-A2 | TARGETS FOR RETROVIRUS ASSOCIATED DISEASES | Université de Liège (BE) | 2011-01-06 | — | — | WO | disclosed |