SCHEMBL9924923

SCHEMBL9924923

CCOc1ccc(-c2ccc(C3CCC4CC(COc5ccc(OCC)c(F)c5F)CCC4C3)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 4/20 0.35
KDM1A O60341 2/20 0.35
RAB9A P51151 1/20 0.34
DGAT1 O75907 1/20 0.34
SSTR5 P35346 2/20 0.33
KCNH2 Q12809 1/20 0.33
FFAR4 Q5NUL3 1/20 0.33
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
FFAR1 O14842 1/20 0.32
PPARD Q03181 1/20 0.32
ALDH1A1 P00352 1/20 0.31
NQO1 P15559 1/20 0.31
PTGIR P43119 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9924789 0.97 KDM1A (0.37) SCN9AKDM1ARAB9ASLC6A2SLC6A4
SCHEMBL9924924 0.94 RAB9A (0.43) SCN9AKDM1ARAB9A
SCHEMBL9925132 0.92 SCN9A (0.35) SCN9AKDM1ARAB9AFFAR4SLC6A2
SCHEMBL9924901 0.91 SCN9A (0.38) SCN9AKDM1ARAB9ASLC6A2SLC6A4
SCHEMBL9924790 0.90 RAB9A (0.45) SCN9AKDM1ARAB9AKCNH2
SCHEMBL19188700 0.90 DRD2 (0.36) SCN9AKDM1ARAB9ASLC6A2SLC6A4
SCHEMBL9924954 0.88 CYP2C9 (0.36) SCN9AKDM1ARAB9ASSTR5KCNH2
SCHEMBL9924918 0.88 SCN9A (0.34) SCN9AKDM1ASSTR5KCNH2FFAR4
SCHEMBL9924781 0.87 MEN1 (0.41) SCN9AKDM1A
SCHEMBL9925096 0.87 RAB9A (0.35) SCN9AKDM1ARAB9ASSTR5KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2468707-B1 DECAHYDRONAPHTHALENE COMPOUNDS, LIQUID CRYSTAL COMPOSITIONS CONTAINING THE COMPOUNDS, AND LIQUID CRYSTAL DISPLAY DEVICES CONTAINING THE LIQUID CRYSTAL COMPOSITIONS JNC CORP (JP) 2017-08-02 EP disclosed
US-8465674-B2 Decahydronaphthalene compound, liquid crystal composition including the compound and liquid crystal display device containing the liquid crystal composition JNC CORPORATION (JP) 2013-06-18 US disclosed
US-8465674-B2 Decahydronaphthalene compound, liquid crystal composition including the compound and liquid crystal display device containing the liquid crystal composition JNC CORPORATION (JP) 2013-06-18 US disclosed
EP-2468707-A1 DECAHYDRONAPHTHALENE COMPOUNDS, LIQUID CRYSTAL COMPOSITIONS CONTAINING THE COMPOUNDS, AND LIQUID CRYSTAL DISPLAY ELEMENTS CONTAINING THE LIQUID CRYSTAL COMPOSITIONS JNC Corporation (JP) 2012-06-27 EP disclosed
US-20120145959-A1 DECAHYDRONAPHTHALENE COMPOUND, LIQUID CRYSTAL COMPOSITION INCLUDING THE COMPOUND AND LIQUID CRYSTAL DISPLAY DEVICE CONTAINING THE LIQUID CRYSTAL COMPOSITION JNC PETROCHEMICAL CORPORATION (JP) 2012-06-14 US disclosed
US-20120145959-A1 DECAHYDRONAPHTHALENE COMPOUND, LIQUID CRYSTAL COMPOSITION INCLUDING THE COMPOUND AND LIQUID CRYSTAL DISPLAY DEVICE CONTAINING THE LIQUID CRYSTAL COMPOSITION JNC PETROCHEMICAL CORPORATION (JP) 2012-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120145959-A1 DECAHYDRONAPHTHALENE COMPOUND, LIQUID CRYSTAL COMPOSITION INCLUDING THE COMPOUND AND LIQUID CRYSTAL DISPLAY DEVICE CONTAINING THE LIQUID CRYSTAL COMPOSITION DCUN1D2, OCIAD1, CPNE4 SCN9A 3847/4885KDM1A 1725/4885RAB9A 4571/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.