Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | PDE8B | O95263 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140381 | 0.86 | ELANE (0.56) | L3MBTL1PTGDR2ELANEGAAKMT2A | |
| SCHEMBL20140783 | 0.84 | L3MBTL1 (0.63) | L3MBTL1CNR1CNR2PTGDR2ELANE | |
| SCHEMBL20140374 | 0.84 | L3MBTL1 (0.49) | L3MBTL1MAPTPTGDR2ELANEKDM4E | |
| SCHEMBL10126766 | 0.81 | PTGDR2 (0.48) | L3MBTL1MAPTTHRBCNR1CNR2 | |
| SCHEMBL14842958 | 0.81 | CNR2 (0.62) | L3MBTL1CNR1CNR2PDE8BLMNA | |
| SCHEMBL31512385 | 0.81 | CNR2 (0.62) | L3MBTL1CNR1CNR2PDE8BLMNA | |
| SCHEMBL4666470 | 0.81 | MAPT (0.54) | L3MBTL1MAPTTHRBCNR1CNR2 | |
| SCHEMBL19798298 | 0.81 | L3MBTL1 (0.52) | L3MBTL1MAPTTHRBCNR1CNR2 | |
| SCHEMBL13733152 | 0.80 | PDE5A (0.53) | MAPTCNR1CNR2PDE8BLMNA | |
| SCHEMBL28098667 | 0.80 | L3MBTL1 (0.51) | L3MBTL1MAPTTHRBCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012075678-A1 | SUBSTITUTED THIAZOLYL PYRAZOLO PYRIDINE COMPOUND AND MEDICINAL USE THEREOF | 中国人民解放军军事医学科学院毒物药物研究所 (CN) | 2012-06-14 | — | — | WO | disclosed |