Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 7/20 | 0.36 |
| ▸ | PDE2A | O00408 | 6/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9925358 | 0.91 | FABP3 (0.38) | KDM4EKMT2AALDH1A1FABP3FABP4 | |
| SCHEMBL12874527 | 0.87 | KDM4E (0.43) | HTR5AKDM4EKMT2AALDH1A1FABP3 | |
| SCHEMBL12874494 | 0.87 | HTR5A (0.47) | HTR5AKDM4EKMT2AALDH1A1FABP3 | |
| SCHEMBL9907632 | 0.84 | KMT2A (0.49) | HTR5AKDM4EKMT2AALDH1A1FABP3 | |
| SCHEMBL15500546 | 0.81 | KDM4E (0.42) | HTR5AKDM4EKMT2AALDH1A1FABP3 | |
| SCHEMBL9907898 | 0.80 | HTR5A (0.64) | HTR5AKMT2A | |
| SCHEMBL9907624 | 0.79 | ALDH1A1 (0.58) | KDM4EKMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL15500555 | 0.77 | ESR2 (0.40) | KDM4EKMT2AALDH1A1FABP3FABP4 | |
| SCHEMBL9907721 | 0.75 | ALDH1A1 (0.50) | KDM4EKMT2AALDH1A1FABP3FABP4 | |
| SCHEMBL12875058 | 0.73 | HTR5A (0.55) | HTR5ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2463276-A1 | NITROGENOUS-RING ACYLGUANIDINE DERIVATIVE | Astellas Pharma Inc. (JP) | 2012-06-13 | — | — | EP | disclosed |