Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 10/20 | 0.60 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.51 |
| ▸ | HTR1A | P08908 | 6/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30493303 | 0.84 | HTR2C (0.72) | HTR2CSLC18A3SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL2653821 | 0.84 | CHRNB4 (0.41) | HTR2CSLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL7450882 | 0.80 | HTR1A (0.42) | HTR2CSLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL23735529 | 0.78 | PTGDR2 (0.42) | HTR2CHTR1A | |
| SCHEMBL5887373 | 0.78 | PTGDR2 (0.42) | HTR2CHTR1A | |
| SCHEMBL11836887 | 0.75 | HTR2C (0.60) | HTR2CSLC18A3SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL1513258 | 0.75 | HTR2C (1.00) | HTR2CSLC18A3SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL233327 | 0.75 | HTR1A (0.61) | HTR2CSLC18A3SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL14879859 | 0.75 | HTR2C (0.60) | HTR2CSLC18A3SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL5584664 | 0.75 | HTR2C (0.60) | HTR2CSLC18A3SIGMAR1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2228049-B1 | Dental composition | DENTSPLY DETREY GMBH (DE) | 2016-11-09 | — | — | EP | disclosed |
| US-20120149801-A1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2012-06-14 | — | — | US | disclosed |
| US-20120149801-A1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2012-06-14 | — | — | US | disclosed |
| WO-2010102786-A1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2010-09-16 | — | — | WO | disclosed |
| EP-2228049-A1 | Dental composition | Dentsply DeTrey GmbH (DE) | 2010-09-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149801-A1 | DENTAL COMPOSITION | SMCHD1, GGH, DDX3X | HTR2C 4783/4885SLC18A3 4297/4885SIGMAR1 2201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.