Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.45 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18117438 | 0.81 | MAPT (0.36) | MAOAMAOBACHEHTR2C | |
| SCHEMBL8295568 | 0.78 | MAPT (0.35) | — | |
| SCHEMBL9925856 | 0.77 | ALDH1A1 (0.36) | MAOAKDM1AMAOBRAB9AKMT2A | |
| SCHEMBL9925876 | 0.75 | ALDH1A1 (0.38) | KDM1ARAB9AKMT2AMEN1TP53 | |
| SCHEMBL1515875 | 0.66 | CA1 (0.52) | MAOAKDM1AMAOBCA12CA1 | |
| SCHEMBL11971251 | 0.66 | MAP2K1 (0.53) | MAOAKDM1AMAOBMAP2K1RAB9A | |
| SCHEMBL9620268 | 0.66 | KDM1A (0.47) | MAOAKDM1AMAOBMAP2K1CA12 | |
| SCHEMBL9620266 | 0.66 | KDM1A (0.47) | MAOAKDM1AMAOBMAP2K1CA12 | |
| SCHEMBL9359327 | 0.66 | MAOA (0.58) | MAOAKDM1AMAOBMAP2K1CA12 | |
| SCHEMBL11971054 | 0.66 | MAP2K1 (0.53) | MAOAKDM1AMAOBMAP2K1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1618087-B1 | ANTIBACTERIAL AGENTS | NOVARTIS VACCINES & DIAGNOSTIC (US) | 2012-06-13 | — | — | EP | disclosed |
| EP-2295402-A2 | Antibacterial agents | The University of Washington (US) | 2011-03-16 | — | — | EP | disclosed |