Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | ANPEP | P15144 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | DBH | P09172 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TOP1 | P11387 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | TERT | O14746 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL402442 | 0.83 | CA2 (0.48) | ANPEPCA2CA1CA12CA7 | |
| SCHEMBL1109351 | 0.82 | POLB (0.45) | HDAC6ANPEPKDM4ETOP1 | |
| SCHEMBL5450568 | 0.81 | CA2 (0.49) | ANPEPCA2CA1 | |
| SCHEMBL405181 | 0.81 | CA2 (0.49) | ANPEPCA2CA1 | |
| SCHEMBL402851 | 0.81 | CCR1 (0.47) | HDAC6ANPEPPDE4APDE4BPDE4C | |
| SCHEMBL405477 | 0.81 | CCR1 (0.47) | HDAC6ANPEPPDE4APDE4BPDE4C | |
| SCHEMBL1912251 | 0.81 | HDAC1 (0.44) | HDAC6ANPEP | |
| SCHEMBL403058 | 0.80 | CA2 (0.51) | CA2CA1 | |
| SCHEMBL398439 | 0.80 | ALDH1A1 (0.53) | CA2CA1CA12CA14 | |
| SCHEMBL12055901 | 0.80 | NPC1 (0.48) | CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1618087-B1 | ANTIBACTERIAL AGENTS | NOVARTIS VACCINES & DIAGNOSTIC (US) | 2012-06-13 | — | — | EP | disclosed |
| EP-2295402-A2 | Antibacterial agents | The University of Washington (US) | 2011-03-16 | — | — | EP | disclosed |