Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 5/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | LSS | P48449 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.41 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1105484 | 0.81 | CHRM2 (0.45) | CHRM4CHRM2CHRM1SCN9AFAAH | |
| SCHEMBL12064329 | 0.81 | CHRM2 (0.45) | CHRM4CHRM2CHRM1SCN9AFAAH | |
| SCHEMBL1109081 | 0.81 | CHRM2 (0.45) | CHRM4CHRM2CHRM1SCN9AFAAH | |
| SCHEMBL402540 | 0.80 | CHRM2 (0.40) | CHRM4CHRM2CHRM1LSSPTGDR2 | |
| SCHEMBL1109146 | 0.80 | HSD11B1 (0.50) | CHRM2CHRM1PTGDR2HRH3FAAH | |
| SCHEMBL399384 | 0.80 | HSD11B1 (0.50) | CHRM2CHRM1PTGDR2HRH3FAAH | |
| SCHEMBL12064387 | 0.80 | HSD11B1 (0.50) | CHRM2CHRM1PTGDR2HRH3FAAH | |
| SCHEMBL9903924 | 0.73 | MMP13 (0.47) | HRH3EPHX2PDE4B | |
| SCHEMBL2692091 | 0.73 | MMP13 (0.47) | HRH3EPHX2PDE4B | |
| SCHEMBL203227 | 0.73 | MMP13 (0.47) | HRH3EPHX2PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1618087-B1 | ANTIBACTERIAL AGENTS | NOVARTIS VACCINES & DIAGNOSTIC (US) | 2012-06-13 | — | — | EP | disclosed |