SCHEMBL9926147

SCHEMBL9926147

c1ccc2c(c1)Oc1cccc3c4cc(-c5ccc(-c6ccc(-c7ccc8c(c7)c7cccc9c7n8-c7ccccc7O9)cc6)cc5)ccc4n-2c13

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
P2RX4 Q99571 6/20 0.34
PDE4B Q07343 1/20 0.32
EDNRB P24530 1/20 0.32
EDNRA P25101 1/20 0.32
TSPO P30536 1/20 0.31
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
PRKDC P78527 1/20 0.30
PLA2G2A P14555 1/20 0.30
PLA2G4A P47712 1/20 0.30
MAPT P10636 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9926181 1.00 P2RX4 (0.34) P2RX4PDE4BEDNRBEDNRATSPO
SCHEMBL9926167 0.98 P2RX4 (0.35) P2RX4PDE4BEDNRBEDNRATDP1
SCHEMBL9926149 0.97 PRKDC (0.34) P2RX4PDE4BEDNRBEDNRATSPO
SCHEMBL9926144 0.97 PRKDC (0.34) P2RX4PDE4BEDNRBEDNRATSPO
SCHEMBL9926151 0.97 PRKDC (0.34) P2RX4PDE4BEDNRBEDNRATSPO
SCHEMBL9926145 0.97 PRKDC (0.34) P2RX4PDE4BEDNRBEDNRATSPO
SCHEMBL15236796 0.97 P2RX4 (0.36) P2RX4PDE4BEDNRBEDNRATSPO
SCHEMBL20976227 0.96 PRKDC (0.36) P2RX4PDE4BEDNRBEDNRATSPO
SCHEMBL20976228 0.96 PRKDC (0.36) P2RX4PDE4BEDNRBEDNRATSPO
SCHEMBL20976188 0.96 PRKDC (0.36) P2RX4PDE4BEDNRBEDNRATSPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2649080-B1 INDOLOPHENOXAZINE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CANON KK (JP) 2018-04-04 EP disclosed
US-9515270-B2 Indolophenoxazine compound and organic light emitting device using the same CANON KABUSHIKI KAISHA (JP) 2016-12-06 US disclosed
US-9515270-B2 Indolophenoxazine compound and organic light emitting device using the same CANON KABUSHIKI KAISHA (JP) 2016-12-06 US disclosed
US-20130228770-A1 INDOLOPHENOXAZINE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-09-05 US disclosed
US-20130228770-A1 INDOLOPHENOXAZINE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-09-05 US disclosed
WO-2012077582-A1 INDOLOPHENOXAZINE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2012-06-14 WO disclosed