SCHEMBL9926181

SCHEMBL9926181

c1ccc2c(c1)Oc1cccc3c4cc(-c5ccc(-c6ccc7c(c6)c6cccc8c6n7-c6ccccc6O8)cc5)ccc4n-2c13

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
P2RX4 Q99571 6/20 0.34
PDE4B Q07343 1/20 0.32
EDNRB P24530 1/20 0.32
EDNRA P25101 1/20 0.32
TSPO P30536 1/20 0.31
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
PRKDC P78527 1/20 0.30
PLA2G2A P14555 1/20 0.30
PLA2G4A P47712 1/20 0.30
MAPT P10636 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9926147 1.00 P2RX4 (0.34) P2RX4PDE4BEDNRBEDNRATSPO
SCHEMBL9926167 0.98 P2RX4 (0.35) P2RX4PDE4BEDNRBEDNRATDP1
SCHEMBL9926149 0.97 PRKDC (0.34) P2RX4PDE4BEDNRBEDNRATSPO
SCHEMBL9926144 0.97 PRKDC (0.34) P2RX4PDE4BEDNRBEDNRATSPO
SCHEMBL9926151 0.97 PRKDC (0.34) P2RX4PDE4BEDNRBEDNRATSPO
SCHEMBL9926145 0.97 PRKDC (0.34) P2RX4PDE4BEDNRBEDNRATSPO
SCHEMBL15236796 0.97 P2RX4 (0.36) P2RX4PDE4BEDNRBEDNRATSPO
SCHEMBL20976227 0.96 PRKDC (0.36) P2RX4PDE4BEDNRBEDNRATSPO
SCHEMBL20976228 0.96 PRKDC (0.36) P2RX4PDE4BEDNRBEDNRATSPO
SCHEMBL20976188 0.96 PRKDC (0.36) P2RX4PDE4BEDNRBEDNRATSPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210126199-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR SAME SAMSUNG DISPLAY CO., LTD. (KR) 2021-04-29 US disclosed
US-10283718-B2 Charge transporting material, organic electroluminescent element, light emitting device, display device and illumination device UDC IRELAND LIMITED (IE) 2019-05-07 US disclosed
EP-2649080-B1 INDOLOPHENOXAZINE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CANON KK (JP) 2018-04-04 EP disclosed
US-9515270-B2 Indolophenoxazine compound and organic light emitting device using the same CANON KABUSHIKI KAISHA (JP) 2016-12-06 US disclosed
US-9515270-B2 Indolophenoxazine compound and organic light emitting device using the same CANON KABUSHIKI KAISHA (JP) 2016-12-06 US disclosed
US-20130228770-A1 INDOLOPHENOXAZINE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-09-05 US disclosed
US-20130228770-A1 INDOLOPHENOXAZINE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-09-05 US disclosed
WO-2012077582-A1 INDOLOPHENOXAZINE COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2012-06-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10283718-B2 Charge transporting material, organic electroluminescent element, light emitting device, display device and illumination device SLC39A11, GNA11, TMEM109 P2RX4 2733/4885PDE4B 4846/4885EDNRB 3103/4885
US-20210126199-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR SAME TMEM109, SLC16A1, PIEZO1 P2RX4 1572/4885PDE4B 4314/4885EDNRB 2303/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.