Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 8/20 | 0.62 |
| ▸ | TNKS2 | Q9H2K2 | 8/20 | 0.62 |
| ▸ | SULT2A1 | Q06520 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.32 |
| ▸ | VNN1 | O95497 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.32 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.31 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.31 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.31 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.31 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9901468 | 0.92 | TNKS (0.63) | TNKSTNKS2SULT2A1MAOAMAOB | |
| SCHEMBL9901470 | 0.92 | TNKS (0.63) | TNKSTNKS2SULT2A1MAOAMAOB | |
| SCHEMBL9905418 | 0.84 | TNKS (0.52) | TNKSTNKS2SULT2A1MAOAMAOB | |
| SCHEMBL9905416 | 0.84 | TNKS (0.52) | TNKSTNKS2SULT2A1MAOAMAOB | |
| SCHEMBL9926245 | 0.81 | TNKS (0.60) | TNKSTNKS2SULT2A1 | |
| SCHEMBL9926183 | 0.78 | TNKS2 (0.46) | TNKSTNKS2SULT2A1EPHX2PRKAA2 | |
| SCHEMBL9926244 | 0.77 | TNKS (1.00) | TNKSTNKS2SULT2A1MAOAMAOB | |
| SCHEMBL9905220 | 0.76 | TNKS (0.62) | TNKSTNKS2SULT2A1 | |
| SCHEMBL9905223 | 0.76 | TNKS (0.62) | TNKSTNKS2SULT2A1 | |
| SCHEMBL9904973 | 0.75 | TNKS2 (0.43) | TNKSTNKS2SULT2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012076898-A1 | TRIAZOLE DERIVATIVES AS WNT SIGNALING PATHWAY INHIBITORS | OSLO UNIVERSITY HOSPITAL HF (NO) | 2012-06-14 | — | — | WO | disclosed |