Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 8/20 | 0.60 |
| ▸ | TNKS2 | Q9H2K2 | 8/20 | 0.60 |
| ▸ | SULT2A1 | Q06520 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9902076 | 0.90 | TNKS (0.61) | TNKSTNKS2SULT2A1KMT2ACA2 | |
| SCHEMBL9902075 | 0.90 | TNKS (0.61) | TNKSTNKS2SULT2A1KMT2ACA2 | |
| SCHEMBL9926243 | 0.81 | TNKS (0.62) | TNKSTNKS2SULT2A1 | |
| SCHEMBL9905131 | 0.76 | TNKS (0.46) | TNKSTNKS2SULT2A1 | |
| SCHEMBL9905133 | 0.76 | TNKS (0.46) | TNKSTNKS2SULT2A1 | |
| SCHEMBL9926244 | 0.76 | TNKS (1.00) | TNKSTNKS2SULT2A1HPGDCA2 | |
| SCHEMBL15449870 | 0.75 | TNKS (0.46) | TNKSTNKS2SULT2A1KMT2ACA2 | |
| SCHEMBL9905418 | 0.75 | TNKS (0.52) | TNKSTNKS2SULT2A1GAAMAPT | |
| SCHEMBL9905416 | 0.75 | TNKS (0.52) | TNKSTNKS2SULT2A1GAAMAPT | |
| SCHEMBL9901468 | 0.73 | TNKS (0.63) | TNKSTNKS2SULT2A1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012076898-A1 | TRIAZOLE DERIVATIVES AS WNT SIGNALING PATHWAY INHIBITORS | OSLO UNIVERSITY HOSPITAL HF (NO) | 2012-06-14 | — | — | WO | disclosed |