Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3456759 | 0.75 | KDM4E (0.62) | LMNAHTTTDP1ALDH1A1CYP2C19 | |
| SCHEMBL6300684 | 0.75 | KDM4E (0.59) | LMNAHTTPOLBGAATDP1 | |
| SCHEMBL11747954 | 0.73 | HPGD (0.48) | LMNAHTTALDH1A1GLAHPGD | |
| SCHEMBL27210129 | 0.72 | HTT (0.44) | LMNAHTTALDH1A1GLASMN1; SMN2 | |
| SCHEMBL29811259 | 0.72 | HTT (0.44) | LMNAHTTALDH1A1GLASMN1; SMN2 | |
| SCHEMBL3538416 | 0.71 | KDM4E (0.64) | ALDH1A1GLA | |
| SCHEMBL4415935 | 0.70 | LMNA (1.00) | LMNANPSR1HTTPOLBGAA | |
| SCHEMBL11745728 | 0.70 | SMN1; SMN2 (0.52) | LMNAHTTPOLBALDH1A1GLA | |
| SCHEMBL6305077 | 0.70 | ALDH1A1 (0.59) | LMNANPSR1HTTPOLBTDP1 | |
| SCHEMBL11746772 | 0.69 | CYP1A2 (0.45) | LMNAPOLBALDH1A1GLASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012076794-A1 | FUNCTIONALIZATION PROCESSES AND REACTANTS USED IN SUCH PROCESSES USING AN ISATOIC ANHYDRIDE OR A DERIVATIVE THEREOF, BIOLOGICAL MOLECULES THUS TREATED AND KITS | BIOMERIEUX (FR) | 2012-06-14 | — | — | WO | disclosed |