SCHEMBL992674

SCHEMBL992674

Cc1cc(C)c(O)c(-c2c(C)c(C)cc(C)c2O)c1C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
KDM4E B2RXH2 5/20 0.46
MAPT P10636 4/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
USP2 O75604 1/20 0.46
ALDH1A1 P00352 4/20 0.43
HPGD P15428 1/20 0.43
RECQL P46063 1/20 0.43
LMNA P02545 3/20 0.39
GAA P10253 2/20 0.39
MAOA P21397 1/20 0.37
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
TRPA1 O75762 1/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2C9 P11712 2/20 0.36
HTT P42858 2/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29729030 0.79 CA1 (0.50) CA1CA2KDM4EMAPTMEN1
SCHEMBL5680954 0.79 CA1 (0.50) CA1CA2KDM4EMAPTMEN1
SCHEMBL394530 0.79 CA1 (0.50) CA1CA2KDM4EMAPTMEN1
SCHEMBL15485452 0.78 ALDH1A1 (0.47) CA1CA2KDM4EMAPTMEN1
SCHEMBL68382 0.78 CA1 (0.56) CA1CA2KDM4EMAPTMEN1
SCHEMBL204468 0.78 ALDH1A1 (0.47) CA1CA2KDM4EMAPTMEN1
SCHEMBL814919 0.77 CYP3A4 (0.37) CA1CA2MEN1KMT2AALDH1A1
SCHEMBL1243050 0.77 ALDH1A1 (0.41) CA1CA2KDM4EMAPTMEN1
SCHEMBL14973415 0.77 CA1 (0.48) CA1CA2KDM4EMAPTMEN1
SCHEMBL29444800 0.77 CA1 (0.48) CA1CA2KDM4EMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2949638-B1 METHOD FOR THE PREPARATION OF 2,2 -BIPHENOLS USING SELENIUM DIOXIDE EVONIK DEGUSSA GMBH (DE) 2017-11-08 EP disclosed
US-9517986-B2 Process for preparing 2,2′-biphenols using selenium dioxide EVONIK DEGUSSA GMBH (DE) 2016-12-13 US disclosed
US-9517986-B2 Process for preparing 2,2′-biphenols using selenium dioxide EVONIK DEGUSSA GMBH (DE) 2016-12-13 US disclosed
EP-2949638-A1 METHOD FOR THE PREPARATION OF 2,2 -BIPHENOLS USING SELENIUM DIOXIDE Evonik Degussa GmbH (DE) 2015-12-02 EP disclosed
US-20150336865-A1 PROCESS FOR PREPARING 2,2'-BIPHENOLS USING SELENIUM DIOXIDE EVONIK DEGUSSA GMBH (DE) 2015-11-26 US disclosed
US-20150336865-A1 PROCESS FOR PREPARING 2,2'-BIPHENOLS USING SELENIUM DIOXIDE EVONIK DEGUSSA GMBH (DE) 2015-11-26 US disclosed
EP-2277623-A2 Polymeric phosphorus-containing compositions and their use in hydrocyanation, unsaturated nitrile isomerization and hydroformylation reactions INVISTA Technologies S.à.r.l. (CH) 2011-01-26 EP disclosed
EP-2277623-A2 Polymeric phosphorus-containing compositions and their use in hydrocyanation, unsaturated nitrile isomerization and hydroformylation reactions INVISTA Technologies S.à.r.l. (CH) 2011-01-26 EP disclosed
EP-1586598-B1 Process for preparation of polymeric, phosphorus-containing compositions INVISTA TECH SARL (CH) 2009-09-09 EP disclosed
EP-1571172-B1 Polymeric, phosphorus-containing compositions and their use in hydrocyanation, isomerization and hydroformylation reactions INVISTA TECH SARL (CH) 2008-10-22 EP disclosed
US-6284865-B1 POLYESTER OR POLYAMIDE CONTAINING PHOSPHITE GROUPS PREPARED FROM AN AROMATIC DIHYDROXYPOLYCARBOXYLIC ACID, A POLYOL OR DIAMINE AND A PHOSPHOROCHLORIDITE E. I. DU PONT DE NEMOURS AND COMPANY 2001-09-04 US disclosed
WO-2001021567-A2 HYDROFORMYLATION PROCESS UTILIZING MULTIDENTATE PHOSPHITE LIGANDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-03-29 WO disclosed
WO-2001021627-A1 HYDROFORMYLATION USING MULTIDENTATE PHOSPHITE LIGANDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-03-29 WO disclosed
WO-2001021580-A1 MULTIDENTATE PHOSPHITE LIGANDS, CATALYTIC COMPOSITIONS CONTAINING SUCH LIGANDS AND CATALYTIC PROCESSES UTILIZING SUCH CATALYTIC COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-03-29 WO disclosed
WO-2001021308-A1 HYDROFORMYLATION OF UNSATURATED COMPOUNDS USING POLYMERIC PHOSPHITE LIGANDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-03-29 WO disclosed
WO-2001021684-A1 POLYMERIC PHOSPHITE COMPOSITION AND HYDROCYANATION OF UNSATURATED ORGANIC COMPOUNDS AND THE ISOMERIZATION OF UNSATURATED NITRILES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-03-29 WO disclosed
US-6171996-B1 Hydrocyanation processes and multidentate phosphite ligand and nickel catalyst compositions therefor E. I. DU PONT DE NEMOURS AND COMPANY 2001-01-09 US disclosed
US-6127567-A HYDROCYANATION OF AN ALIPHATIC MONOETHYLENICALLY UNSATURATED COMPOUND, USING A CATALYST PRECURSOR COMPOSITION OF ZERO-VALENT NICKEL, A LEWIS ACID, AND A MULTIDENTATE PHOSPHITE LIGAND OF GIVEN FORMULA; CATALYST SELECTIVITY E. I. DU PONT DE NEMOURS AND COMPANY (US) 2000-10-03 US disclosed
EP-1000022-A1 HYDROCYANATION PROCESSES AND MULTIDENTATE PHOSPHITE LIGAND AND NICKEL CATALYST COMPOSITIONS THEREFOR E.I. DU PONT DE NEMOURS & COMPANY INCORPORATED (US) 2000-05-17 EP disclosed
WO-1999006358-A1 HYDROCYANATION PROCESSES AND MULTIDENTATE PHOSPHITE LIGAND AND NICKEL CATALYST COMPOSITIONS THEREFOR E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-02-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150336865-A1 PROCESS FOR PREPARING 2,2'-BIPHENOLS USING SELENIUM DIOXIDE SELENOI, PLK1, BPGM CA1 1654/4885CA2 431/4885KDM4E 1529/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.