Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 16/20 | 0.41 |
| ▸ | CTSA | P10619 | 2/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9929633 | 0.84 | PIK3CD (0.47) | PIK3CD | |
| SCHEMBL9952247 | 0.83 | PIK3CD (0.46) | PIK3CDCTSAAPLNR | |
| Hydrochloric Acid SCHEMBL9929471 | 0.83 | PIK3CD (0.46) | PIK3CDCTSA | |
| SCHEMBL17333074 | 0.82 | PIK3CD (0.58) | PIK3CD | |
| SCHEMBL9953244 | 0.74 | PIK3CD (0.37) | PIK3CDCTSAAPLNRCNR2 | |
| SCHEMBL9952249 | 0.73 | HCRTR1 (0.38) | PIK3CDCTSAAPLNRCNR2 | |
| SCHEMBL17333103 | 0.73 | IMPDH2 (0.32) | — | |
| SCHEMBL9928938 | 0.73 | IMPDH2 (0.32) | — | |
| SCHEMBL9928708 | 0.73 | PIK3CD (0.37) | PIK3CDCTSACNR2 | |
| SCHEMBL9929169 | 0.72 | PIK3CD (0.54) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120157430-A1 | N-(1-(SUBSTITUTED-PHENYL)ETHYL)-9H-PURIN-6-AMINES AS PI3K INHIBITORS | INCYTE CORPORATION | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157430-A1 | N-(1-(SUBSTITUTED-PHENYL)ETHYL)-9H-PURIN-6-AMINES AS PI3K INHIBITORS | PIK3CA, PIK3CD, PI4KB | PIK3CD 2/4885CTSA 3128/4885APLNR 869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.