SCHEMBL9929222

SCHEMBL9929222

CC1=Nc2ccc3c(S(=O)(=O)O)cc(S(=O)(=O)O)cc3c2C1(C)CCCS(=O)(=O)O.[KH].[KH].[KH]

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL133416 0.99 FOLH1 (0.32) FOLH1
SCHEMBL29331376 0.85 FOLH1 (0.32) FOLH1
SCHEMBL101318 0.84 MEN1 (0.36)
SCHEMBL14781529 0.82 FOLH1 (0.35) FOLH1
SCHEMBL28003086 0.81
SCHEMBL14695213 0.81 MEN1 (0.43) FOLH1
SCHEMBL136734 0.79 MEN1 (0.44) FOLH1
SCHEMBL29017325 0.78 RXRA (0.30)
SCHEMBL9929142 0.78 RXRA (0.30)
Potassium Ion SCHEMBL9929223 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11053222-B2 Fluorescent compounds PIERCE BIOTECHNOLOGY, INC. (US) 2021-07-06 US disclosed
US-10696653-B2 Cyanine compounds PIERCE BIOTECHNOLOGY, INC. (US) 2020-06-30 US disclosed
US-10351551-B2 Fluorescent compounds PIERCE BIOTECHNOLOGY, INC. (US) 2019-07-16 US disclosed
EP-3081564-B1 INDOLE DERIVATIVES AS LABELING DYE FOR BIOMOLECULE PIERCE BIOTECHNOLOGY INC (US) 2019-07-10 EP disclosed
US-20180327387-A1 Cyanine Compounds PIERCE BIOTECHNOLOGY, INC. (US) 2018-11-15 US disclosed
US-10053447-B2 Fluorescent compounds PIERCE BIOTECHNOLOGY, INC (US) 2018-08-21 US disclosed
EP-3029027-B1 FLUORESCENT COMPOUNDS PIERCE BIOTECHNOLOGY INC (US) 2018-06-27 EP disclosed
US-20180118723-A1 FLUORESCENT COMPOUNDS PIERCE BIOTECHNOLOGY, INC. (US) 2018-05-03 US disclosed
US-20170158858-A9 CYANINE COMPOUNDS PIERCE BIOTECHNOLOGY, INC. 2017-06-08 US disclosed
US-20170114038-A9 CYANINE COMPOUNDS PIERCE BIOTECHNOLOGY, INC. 2017-04-27 US disclosed
US-20160168383-A1 CYANINE COMPOUNDS HERMANSON GREG (US) 2016-06-16 US disclosed
EP-2804860-B1 INDOLE DERIVATIVES AS LABELING DYE FOR BIOMOLECULE PIERCE BIOTECHNOLOGY INC (US) 2016-06-15 EP disclosed
EP-3029027-A1 FLUORESCENT COMPOUNDS Pierce Biotechnology, Inc. (US) 2016-06-08 EP disclosed
EP-2655327-B1 FLUORESCENT COMPOUNDS PIERCE BIOTECHNOLOGY INC (US) 2016-02-24 EP disclosed
US-20140255312-A1 CYANINE COMPOUNDS PIERCE BIOTECHNOLOGY, INC. 2014-09-11 US disclosed
US-20140072515-A9 CYANINE COMPOUNDS PIERCE BIOTECHNOLOGY, INC. 2014-03-13 US disclosed
US-20130251637-A9 FLUORESCENT COMPOUNDS DYOMICS GMBH (DE) 2013-09-26 US disclosed
US-20130230466-A1 CYANINE COMPOUNDS HERMANSON GREG (US) 2013-09-05 US disclosed
US-20120294807-A9 FLUORESCENT COMPOUNDS DYOMICS GMBH (DE) 2012-11-22 US disclosed
US-20120156140-A1 FLUORESCENT COMPOUNDS DYOMICS GMBH (DE) 2012-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (15 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170158858-A9 CYANINE COMPOUNDS NCL, NOP58, NAT10 FOLH1 3057/4885
US-20180118723-A1 FLUORESCENT COMPOUNDS NCL, FUS, EFTUD2 FOLH1 894/4885
US-10351551-B2 Fluorescent compounds NCL, FUS, EFTUD2 FOLH1 894/4885
US-20180327387-A1 Cyanine Compounds NCL, NOP58, NAT10 FOLH1 3057/4885
US-20140255312-A1 CYANINE COMPOUNDS NCL, NOP58, NAT10 FOLH1 3057/4885
US-20120156140-A1 FLUORESCENT COMPOUNDS NCL, FUS, EFTUD2 FOLH1 894/4885
US-10696653-B2 Cyanine compounds NCL, NOP58, NAT10 FOLH1 3057/4885
US-20170114038-A9 CYANINE COMPOUNDS NCL, NOP58, NAT10 FOLH1 3057/4885
US-20130230466-A1 CYANINE COMPOUNDS NCL, NOP58, NAT10 FOLH1 3057/4885
US-11053222-B2 Fluorescent compounds NCL, FUS, EFTUD2 FOLH1 894/4885
US-20130251637-A9 FLUORESCENT COMPOUNDS NCL, FUS, EFTUD2 FOLH1 894/4885
US-10053447-B2 Fluorescent compounds NCL, FUS, EFTUD2 FOLH1 894/4885
US-20120294807-A9 FLUORESCENT COMPOUNDS NCL, FUS, EFTUD2 FOLH1 894/4885
US-20160168383-A1 CYANINE COMPOUNDS NCL, NOP58, NAT10 FOLH1 3057/4885
US-20140072515-A9 CYANINE COMPOUNDS NCL, NOP58, NAT10 FOLH1 3057/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.