⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Monoethanolamine SCHEMBL28084893 | 0.93 | MAOA (0.59) | — | |
| Urea SCHEMBL28111873 | 0.89 | MAOA (0.55) | — | |
| SCHEMBL8447495 | 0.89 | MAOA (0.50) | — | |
| SCHEMBL5233047 | 0.85 | MAOA (0.61) | — | |
| SCHEMBL7621771 | 0.85 | MAOA (0.47) | — | |
| SCHEMBL28866669 | 0.84 | — | — | |
| SCHEMBL4780532 | 0.82 | MAOA (0.40) | — | |
| Diethanolamine SCHEMBL27879356 | 0.80 | ALDH1A1 (0.35) | — | |
| SCHEMBL5930720 | 0.79 | — | — | |
| Diethanolamine SCHEMBL8571462 | 0.79 | ALDH1A1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250353821-A1 | BENZENE SULFONAMIDE THIAZOLE COMPOUNDS AND THEIR USE FOR THE TREATMENT OF CANCERS | INST NAT SANTE RECH MED (FR) | 2025-11-20 | — | — | US | claimed |
| CN-119798223-A | (1H-indazol-5-yl) amino-2-pyridine derivative and application thereof | 沈阳药科大学 | 2025-04-11 | — | — | CN | claimed |
| EP-4452956-A1 | BENZENE SULFONAMIDE THIAZOLE COMPOUNDS AND THEIR USE FOR THE TREATMENT OF CANCERS | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2024-10-30 | — | — | EP | claimed |
| CN-118574812-A | Benzenesulfonamide thiazole compounds and their use for the treatment of cancer | 国家医疗保健研究所 | 2024-08-30 | — | — | CN | claimed |
| WO-2023118373-A1 | BENZENE SULFONAMIDE THIAZOLE COMPOUNDS AND THEIR USE FOR THE TREATMENT OF CANCERS | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2023-06-29 | — | — | WO | claimed |
| EP-4201928-A1 | BENZENE SULFONAMIDE THIAZOLE COMPOUNDS AND THEIR USE FOR THE TREATMENT OF CANCERS | Institut National de la Santé et de la Recherche Médicale (INSERM) (FR) | 2023-06-28 | — | — | EP | claimed |
| US-20170166523-A9 | MEK Inhibitors And Methods Of Their Use | EXELIXIS, INC. | 2017-06-15 | — | — | US | claimed |
| US-20150315142-A1 | PROCESS TO OBTAIN IMIDAZOLINE MIXTURES FROM VEGETABLE OILS | CORROSION Y PROTECCION SA DE CV (MX) | 2015-11-05 | — | — | US | claimed |
| US-20150141399-A1 | MEK Inhibitors And Methods Of Their Use | EXELIXIS INC (US) | 2015-05-21 | — | — | US | claimed |
| EP-2454257-A1 | PYRROLOPYRIDINE INHIBITORS OF KINASES | Abbott Laboratories (US) | 2012-05-23 | — | — | EP | claimed |
| US-20090012126-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. | 2009-01-08 | — | — | US | claimed |
| US-20080139575-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. | 2008-06-12 | — | — | US | claimed |
| US-20080132545-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. | 2008-06-05 | — | — | US | claimed |
| WO-2008016643-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-02-07 | — | — | WO | claimed |
| CN-1980661-A | Cationic bacteriochlorophyll derivatives and uses thereof | YEDA RES & DEV (IL) | 2007-06-13 | — | — | CN | claimed |
| US-7030216-B2 | Peptoids incorporating chemoselective functionalities | CHIRON CORPORATION (US) | 2006-04-18 | — | — | US | claimed |
| US-20020169281-A1 | Peptoids incorporating chemoselective functionalities | CHIRON CORPORATION | 2002-11-14 | — | — | US | claimed |
| WO-2002081637-A2 | PEPTIDES INCORPORATING CHEMOSELECTIVE FUNCTIONALITIES | CHIRON CORPORATION (US) | 2002-10-17 | — | — | WO | claimed |
| EP-0567066-B1 | Resin composition for aqueous paints | KANSAI PAINT CO LTD (JP) | 2000-07-12 | — | — | EP | claimed |
| EP-0591984-B1 | Resin composition for aqueous paint | KANSAI PAINT CO LTD (JP) | 1997-07-09 | — | — | EP | claimed |