SCHEMBL992990

SCHEMBL992990

NCC(=O)NCCO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28669812 0.97
Hydrochloric Acid SCHEMBL19926678 0.97
Oxalic Acid SCHEMBL9795096 0.93 ALDH1A1 (0.39)
SCHEMBL3074874 0.85 CA2 (0.44)
SCHEMBL2899419 0.84
SCHEMBL10957270 0.80 ALDH1A1 (0.50)
SCHEMBL12660515 0.80 MEN1 (0.48)
SCHEMBL152135 0.80
SCHEMBL16853212 0.80 ALDH1A1 (0.55)
SCHEMBL5469546 0.79 ALDH1A1 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111643496-A Methods of using MEK inhibitors 埃克塞利希斯股份有限公司 2020-09-11 CN claimed
WO-2018136772-A1 SPERM PROCESSING METHOD, APPARATUS AND RELATED MEDIA COMPOSITIONS INGURAN, LLC (US) 2018-07-26 WO claimed
US-20180208894-A1 SPERM PROCESSING METHOD, APPARATUS AND RELATED MEDIA COMPOSITIONS INGURAN, LLC (US) 2018-07-26 US claimed
CN-105106199-A Methods of using MEK inhibitors EXELIXIS INC 2015-12-02 CN claimed
CN-102472985-B Resist stripping solution composition, and method for stripping resist by using same DONGWOO FINE CHEM CO LTD 2014-01-08 CN claimed
EP-1951686-B1 QUINAZOLINE DERIVATIVES AS A MULTIPLEX INHIBITOR AND METHOD FOR THE PREPARATION THEREOF HANMI PHARM IND CO LTD (KR) 2013-04-03 EP claimed
EP-2454257-A1 PYRROLOPYRIDINE INHIBITORS OF KINASES Abbott Laboratories (US) 2012-05-23 EP claimed
CN-102472985-A Photoresist stripping liquid composition and method for stripping photoresist by using same DONGWOO FINE CHEM CO LTD 2012-05-23 CN claimed
US-20110207712-A1 Phosphatidylinositol 3-Kinase Inhibitors And Methods Of Their Use EXELIXIS, INC. (US) 2011-08-25 US claimed
WO-2011008915-A1 PYRROLOPYRIDINE INHIBITORS OF KINASES ABBOTT LABORATORIES (US) 2011-01-20 WO claimed
US-20110015173-A1 PYRROLOPYRIDINE INHIBITORS OF KINASES ABBOTT LABORATORIES (US) 2011-01-20 US claimed
CN-101605540-A Methods of using MEK inhibitors EXELIXIS INC (US) 2009-12-16 CN claimed
US-20080318950-A1 Quinazoline Derivatives as a Multiplex Inhibitor and Method For the Preparation Thereof HANMI PHARM. CO., LTD (KR) 2008-12-25 US claimed
EP-1951686-A1 QUINAZOLINE DERIVATIVES AS A MULTIPLEX INHIBITOR AND METHOD FOR THE PREPARATION THEREOF Hanmi Pharm. Co., Ltd. (KR) 2008-08-06 EP claimed
WO-2007055514-A1 QUINAZOLINE DERIVATIVES AS A MULTIPLEX INHIBITOR AND METHOD FOR THE PREPARATION THEREOF HANMI PHARM. CO., LTD. (KR) 2007-05-18 WO claimed
US-5430133-A Semi-synthetic glycosaminoglycans with heparin or heparan structure of α-L-iduronic-2-O-sulfate acid modified in position 2 ALFA WASSERMANN S.P.A. (IT) 1995-07-04 US claimed
US-5410039-A Process for the synthesis of glycosaminoglycans containing α-L-galacturonic acid substituted with nucleophilic groups in position 3 ALFA WASSERMANN S.P.A. (IT) 1995-04-25 US claimed
US-5405949-A Process for the synthesis of glycosaminoglycans with heparin or heparan structure modified in position 2 of the α-L-iduronic-2-O-sulfate acid ALFA WASSERNANN S.P.A. (IT) 1995-04-11 US claimed
EP-4731602-A1 NEW CLASS OF LIPIDS FOR DELIVERING ACTIVE INGREDIENTS INTO CELLS OZ Biosciences (FR) 2026-04-29 EP disclosed
US-4613676-A PEPTIDES CIBA-GEIGY CORPORATION (US) 1986-09-23 US disclosed