SCHEMBL9929994

SCHEMBL9929994

O=C1C(=O)c2cc(S(=O)(=O)O)ccc2-c2ccc(S(=O)(=O)O)cc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 3/20 0.48
ALDH1A1 P00352 7/20 0.47
GAA P10253 2/20 0.47
HSD17B10 Q99714 4/20 0.47
LMNA P02545 1/20 0.46
APEX1 P27695 2/20 0.46
S100A4 P26447 3/20 0.44
TSHR P16473 3/20 0.44
NT5E P21589 1/20 0.44
TDP1 Q9NUW8 2/20 0.44
MEN1 O00255 1/20 0.44
THRB P10828 1/20 0.44
RECQL P46063 1/20 0.44
BLM P54132 1/20 0.44
KMT2A Q03164 1/20 0.44
PTPRC P08575 1/20 0.43
POLB P06746 1/20 0.42
KDM4E B2RXH2 1/20 0.42
HPGD P15428 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15314924 0.95 PKM (0.53) PKMALDH1A1GAAHSD17B10LMNA
SCHEMBL23357768 0.93 PKM (0.52) PKMALDH1A1GAAHSD17B10LMNA
SCHEMBL2553104 0.93 PKM (0.52) PKMALDH1A1GAAHSD17B10LMNA
SCHEMBL6665982 0.92 PTPRC (0.52) PKMALDH1A1LMNAS100A4TSHR
SCHEMBL29490328 0.91 ESR1 (0.50) PKMALDH1A1GAAHSD17B10LMNA
SCHEMBL31059305 0.91 ESR1 (0.50) PKMALDH1A1GAAHSD17B10LMNA
SCHEMBL29561433 0.91 ESR1 (0.50) PKMALDH1A1GAAHSD17B10LMNA
SCHEMBL29600607 0.91 ESR1 (0.50) PKMALDH1A1GAAHSD17B10LMNA
SCHEMBL517673 0.91 ESR1 (0.50) PKMALDH1A1GAAHSD17B10LMNA
SCHEMBL1782510 0.91 ESR1 (0.50) PKMALDH1A1GAAHSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4365213-A1 POLYMER, REAGENT LAYER, AND SENSOR PHC Holdings Corporation (JP) 2024-05-08 EP disclosed
US-20240141404-A1 POLYMER, REAGENT LAYER, AND SENSOR PHC HOLDINGS CORPORATION (JP) 2024-05-02 US disclosed
CN-117616056-A Polymer, reagent layer and sensor 普和希控股公司 2024-02-27 CN disclosed
WO-2024029526-A1 ELECTRODE, SENSOR, AND METHOD FOR PRODUCING SENSOR PHCホールディングス株式会社 2024-02-08 WO disclosed
WO-2024019017-A1 REAGENT LAYER AND BIOSENSOR COMPRISING REAGENT LAYER PHCホールディングス株式会社 2024-01-25 WO disclosed
WO-2024005025-A1 SENSOR AND METHOD FOR MANUFACTURING SAME PHCホールディングス株式会社 2024-01-04 WO disclosed
WO-2023276772-A1 POLYMER, REAGENT LAYER, AND SENSOR PHCホールディングス株式会社 2023-01-05 WO disclosed
US-10761045-B2 Sensor, sensor system, method of manufacturing sensor, and method of measuring concentration of target substance PHC HOLDINGS CORPORATION (JP) 2020-09-01 US disclosed
US-20200080956-A1 SENSOR, SENSOR SYSTEM, METHOD OF MANUFACTURING SENSOR, AND METHOD OF MEASURING CONCENTRATION OF TARGET SUBSTANCE PHC HOLDINGS CORP (JP) 2020-03-12 US disclosed
US-10571424-B2 Sensor, sensor system, method of manufacturing sensor, and method of measuring concentration of target substance PHC HOLDINGS CORPORATION (JP) 2020-02-25 US disclosed
WO-2019187574-A1 BIOSENSOR PHCホールディングス株式会社 2019-10-03 WO disclosed
WO-2019187575-A1 BIOLOGICAL SUBSTANCE DETECTION SENSOR PHCホールディングス株式会社 2019-10-03 WO disclosed
US-9594044-B2 Reagent composition, sensor, sensor system, and sensor manufacture process PANASONIC HEALTHCARE HOLDINGS CO., LTD. (JP) 2017-03-14 US disclosed
US-20160376626-A1 SENSOR, SENSOR SYSTEM, METHOD OF MANUFACTURING SENSOR, AND METHOD OF MEASURING CONCENTRATION OF TARGET SUBSTANCE PHC HOLDINGS CORPORATION (JP) 2016-12-29 US disclosed
US-20130161204-A1 REAGENT COMPOSITION, SENSOR, SENSOR SYSTEM, AND SENSOR MANUFACTURE PROCESS PANASONIC CORPORATION (JP) 2013-06-27 US disclosed
US-20120157434-A1 Antimicrobial heterocyclic compounds for treatment of bacterial infections CSO of MicuRx Pharmaceuticals, Inc. 2012-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120157434-A1 Antimicrobial heterocyclic compounds for treatment of bacterial infections NISCH, NOD1, NQO1 PKM 2339/4885ALDH1A1 953/4885GAA 476/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.